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Found 135 clinical trials|View Analysis
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Nor)Clozapine Kinetics and Side Effects in Therapy Resistant Schizophrenia and the Optimal Sampling Time for Therapeutic Drug Monitoring

Not yet recruiting
Conditions
Cardiovascular Side Effects of Clozapine
Neutropenia Due to Clozapine
General Side Effects of Clozapine
Constipation Due to Clozapine
Symptoms of Schizophrenia
Optimal Blood Sampling Time for Clozapine in Patients Who Receive Clozapine Once and Twice Daily
Clozapine and Norclozapine Plasma Level Concentrations
First Posted Date
2024-12-27
Last Posted Date
2024-12-30
Lead Sponsor
GGZ Noord-Holland-Noord
Target Recruit Count
60
Registration Number
NCT06749041

Research on the Risk Warning Model and Prevention Strategies for Acute Kidney Injury Associated With Cyclosporine Based on Explainable Deep Neural Networks and Therapeutic Drug Monitoring

Active, not recruiting
Conditions
AKI
Therapeutic Drug Monitoring (TDM)
First Posted Date
2024-09-19
Last Posted Date
2024-09-19
Lead Sponsor
Qianfoshan Hospital
Target Recruit Count
1200
Registration Number
NCT06596811
Locations
🇨🇳

The First Affiliated Hospital of Shandong First Medical University & Shandong Provincial Qianfoshan Hospital, Jinan, China

Therapeutic Drug Monitoring for Linezolid in the Treatment of Rifampin-resistant Tuberculosis

Not Applicable
Not yet recruiting
Conditions
Rifampin-resistant Tuberculosis
Drug-resistant Tuberculosis
Interventions
Other: Therapeutic Drug Monitoring for Linezolid
First Posted Date
2024-09-19
Last Posted Date
2024-12-27
Lead Sponsor
Albert Einstein College of Medicine
Target Recruit Count
280
Registration Number
NCT06590428
Locations
🇿🇦

Nkqubela TB Specialist Hospital, East London, Eastern Cape, South Africa

Antimicrobial Therapeutic Drug Monitoring During Lung Transplant Perioperative Phase

Not yet recruiting
Conditions
Lung Transplant Infection
Pneumonia, Bacterial
Antibiotic Resistant Strain
First Posted Date
2024-09-04
Last Posted Date
2024-09-04
Lead Sponsor
Policlinico Hospital
Target Recruit Count
20
Registration Number
NCT06583642
Locations
🇮🇹

Fondazione IRCCS Ca'Granda - Ospedale Maggiore Policlinico, Milan, Italy

Microsampling for Therapeutic Drug Monitoring of Oral Oncolytics in Oncology Patients

Not Applicable
Not yet recruiting
Conditions
Drug Monitoring
Interventions
Diagnostic Test: Therapeutic drug monitoring with a dried blood spot and microatainer.
First Posted Date
2024-08-09
Last Posted Date
2024-08-09
Lead Sponsor
Leiden University Medical Center
Target Recruit Count
360
Registration Number
NCT06545292

Pharmacogenomics for Better Treatment of Fungal Infections in Cancer

Phase 2
Not yet recruiting
Conditions
Haematological Malignancy
Blood Cancer
Infectious Disease
Fungal Infection
Interventions
Other: genotype-directed dosing with dosing software based on therapeutic drug monitoring
First Posted Date
2024-07-19
Last Posted Date
2024-07-19
Lead Sponsor
The University of Queensland
Target Recruit Count
104
Registration Number
NCT06510699
Locations
🇦🇺

Royal Brisbane & Women's Hospital, Brisbane, Queensland, Australia

🇦🇺

Peter MacCallum Cancer Centre, Melbourne, Victoria, Australia

🇦🇺

Sydney Children's Hospital Network, Sydney, New South Wales, Australia

and more 4 locations

Effect of Proactive Therapeutic Drug Monitoring on Maintenance of Sustained Disease Control in Adults With Rheumatoid Arthritis on a Subcutaneous TNF Inhibitor: The Rheumatoid Arthritis Therapeutic DRUg Monitoring Trial (RA-DRUM)

Phase 4
Recruiting
Conditions
Rheumatoid Arthritis
Interventions
Drug: Therapeutic drug monitoring (TDM) of adalimumab
First Posted Date
2024-06-04
Last Posted Date
2024-11-29
Lead Sponsor
Diakonhjemmet Hospital
Target Recruit Count
350
Registration Number
NCT06440629
Locations
🇸🇪

Sahlgrenska Universitetssjukehuset, Gothenburg, Sweden

🇦🇹

Medical University Vienna, Vienna, Austria

🇳🇴

Diakonhjemmet sykehus, Oslo, N-0319, Norway

and more 18 locations

Study on Theraputic Drug Monitoring and Phamacokinetics of Isavuconazole in Children

Not Applicable
Recruiting
Conditions
Aspergillosis Invasive
Mucormycosis
Interventions
Other: Theraputic drug monitoring
Drug: Isavuconazole
First Posted Date
2024-06-04
Last Posted Date
2024-12-13
Lead Sponsor
Shanghai Children's Medical Center
Target Recruit Count
200
Registration Number
NCT06440915
Locations
🇨🇳

Shanghai Children's Medical Center, Shanghai, China

Routinely Collected Clinical Data and Evaluation of Antimicrobial Target Attainment

Recruiting
Conditions
Infections, Bacterial
Pharmacokinetics
Drug Monitoring
Drug-Related Side Effects and Adverse Reactions
First Posted Date
2024-05-23
Last Posted Date
2024-05-23
Lead Sponsor
Imperial College London
Target Recruit Count
323
Registration Number
NCT06427317
Locations
🇬🇧

Imperial College Healthcare NHS Trust, London, United Kingdom

Therapeutic Drug Monitoring-baSed adalimuMab De-escalatiOn in nOn-infecTious cHronic Uveitis

Phase 4
Not yet recruiting
Conditions
Uveitis
Chronic Disease
Interventions
Diagnostic Test: Blood sample
Drug: Adalimumab Injection
First Posted Date
2024-04-30
Last Posted Date
2024-07-22
Lead Sponsor
Centre Hospitalier Universitaire de Saint Etienne
Target Recruit Count
320
Registration Number
NCT06390436
Locations
🇫🇷

CH Avignon, Avignon, France

🇫🇷

CH Le Puy-en-Velay, Le Puy-en-Velay, France

🇫🇷

Chu Montpied, Clermont-Ferrand, France

and more 8 locations
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