Horizon Health Network

Canada

Horizon Therapeutics Ireland Designated Activity Company

Belgium

Horizon Pharmaceuticals, Inc.

United States

Horizon Tool, Inc.

United States

HORIZON THERAPEUTICS IRELAND DAC

Spain

Horizon Therapeutics USA, Inc.

United States

Titan Technology Corp

Creative Medical Technology

United States

GigaCloud Technology

Cayman Islands

SLEEPINNOV TECHNOLOGY

France