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Found 5 clinical trials|View Analysis
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STIL101 for Injection for the Treatment of Locally Advanced, Metastatic or Unresectable Pancreatic Cancer, Colorectal Cancer, Renal Cell Cancer, Cervical Cancer and Melanoma

Phase 1
Not yet recruiting
Conditions
Locally Advanced Cervical Carcinoma
Locally Advanced Colorectal Carcinoma
Locally Advanced Malignant Solid Neoplasm
Locally Advanced Melanoma
Locally Advanced Pancreatic Ductal Adenocarcinoma
Locally Advanced Renal Cell Carcinoma
Metastatic Cervical Carcinoma
Metastatic Colorectal Carcinoma
Metastatic Malignant Solid Neoplasm
Metastatic Melanoma
Interventions
Biological: Aldesleukin
Procedure: Biopsy
Procedure: Biospecimen Collection
Procedure: Computed Tomography
Drug: Cyclophosphamide
Procedure: Excisional Biopsy
Drug: Fludarabine
Procedure: Magnetic Resonance Imaging
Procedure: Standard Treatment
Biological: Therapeutic Tumor Infiltrating Lymphocytes
First Posted Date
2024-10-03
Last Posted Date
2024-10-03
Lead Sponsor
City of Hope Medical Center
Target Recruit Count
12
Registration Number
NCT06626256
Locations
🇺🇸

City of Hope Medical Center, Duarte, California, United States

Fluorescence Image Guided Surgery Followed by Intraoperative Photodynamic Therapy for Improving Local Tumor Control in Patients With Locally Advanced or Recurrent Colorectal Cancer

Phase 1
Recruiting
Conditions
Stage III Colorectal Cancer
Locally Advanced Colorectal Carcinoma
Recurrent Colorectal Carcinoma
Interventions
Drug: Aminolevulinic Acid
Procedure: Biospecimen Collection
Procedure: Computed Tomography
Procedure: Fluorescence-Guided Surgery
Procedure: Magnetic Resonance Imaging
Drug: Photodynamic Therapy
Procedure: Surgical Procedure
First Posted Date
2024-03-13
Last Posted Date
2024-08-05
Lead Sponsor
Roswell Park Cancer Institute
Target Recruit Count
21
Registration Number
NCT06307548
Locations
🇺🇸

Roswell Park Cancer Institute, Buffalo, New York, United States

Cadonilimab + FOLFOX Versus FOLFOX in the Neoadjuvant Treatment of pMMR/MSS Locally Advanced Colorectal Cancer

Phase 2
Recruiting
Conditions
Locally Advanced Colorectal Carcinoma
Interventions
Drug: Cadonilimab
Drug: FOLFOX regimen
First Posted Date
2023-12-04
Last Posted Date
2023-12-04
Lead Sponsor
Cancer Institute and Hospital, Chinese Academy of Medical Sciences
Target Recruit Count
170
Registration Number
NCT06154538
Locations
🇨🇳

Cancer Hospital/ National Cancer Center, Chinese Academy of Medical Sciences, Beijing, Beijing, China

Trifluridine/Tipiracil and Talazoparib for the Treatment of Patients With Locally Advanced or Metastatic Colorectal or Gastroesophageal Cancer

Phase 1
Recruiting
Conditions
Advanced Malignant Solid Neoplasm
Clinical Stage IV Gastroesophageal Junction Adenocarcinoma
Clinical Stage IVB Gastroesophageal Junction Adenocarcinoma A
Locally Advanced Colorectal Carcinoma
Locally Advanced Gastroesophageal Junction Adenocarcinoma
Postneoadjuvant Therapy Stage IIIA Gastroesophageal Junction Adenocarcinoma AJCC v8
Postneoadjuvant Therapy Stage IIIB Gastroesophageal Junction Adenocarcinoma AJCC v8
Postneoadjuvant Therapy Stage IV Gastroesophageal Junction Adenocarcinoma AJCC v8
Postneoadjuvant Therapy Stage IVA Gastroesophageal Junction Adenocarcinoma AJCC v8
Postneoadjuvant Therapy Stage IVB Gastroesophageal Junction Adenocarcinoma AJCC v8
Interventions
First Posted Date
2020-08-12
Last Posted Date
2024-10-04
Lead Sponsor
Roswell Park Cancer Institute
Target Recruit Count
45
Registration Number
NCT04511039
Locations
🇺🇸

Roswell Park Cancer Institute, Buffalo, New York, United States

Clinical Trial to Evaluate Safety and Efficacy of Hyperthermic Intra-peritoneal Chemotherapy (HIPEC) With Mitomycin C Used During Surgery for Treatment of Locally Advanced Colorectal Carcinoma

Phase 3
Active, not recruiting
Conditions
Colorectal Cancer
Interventions
Drug: MITOMYCIN-C 30 mg
Procedure: Proactive cytoreductive surgery
First Posted Date
2015-11-25
Last Posted Date
2023-09-28
Lead Sponsor
Maimónides Biomedical Research Institute of Córdoba
Target Recruit Count
200
Registration Number
NCT02614534
Locations
🇪🇸

Hospital de Sant Joan Despí. Moisès Broggi, Sant Joan Despí, Barcelona, Spain

🇪🇸

Hospital Universitario La Paz, Madrid, Spain

🇪🇸

Hospital Universitario Son Espases, Palma De Mallorca, Islas Baleares, Spain

and more 16 locations
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