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Real-life Treatment Outcomes of Ravulizumab in PNH

Not yet recruiting
Conditions
Paroxysmal Nocturnal Haemoglobinuria
Interventions
First Posted Date
2024-10-09
Last Posted Date
2024-10-09
Lead Sponsor
AstraZeneca
Target Recruit Count
40
Registration Number
NCT06633536

A Study to Compare SB12 (Proposed Eculizumab Biosimilar) to Soliris in Subjects With Paroxysmal Nocturnal Haemoglobinuria

Phase 3
Completed
Conditions
Paroxysmal Nocturnal Hemoglobinuria
Interventions
Drug: SB12 (proposed eculizumab biosimilar)
Drug: Soliris (eculizumab)
First Posted Date
2019-08-15
Last Posted Date
2024-03-26
Lead Sponsor
Samsung Bioepis Co., Ltd.
Target Recruit Count
50
Registration Number
NCT04058158
Locations
🇮🇳

Fortis Memorial Research Institute, Gurgaon, Haryana, India

🇲🇾

Hospital Sultanah Aminah, Johor Bahru, Malaysia

🇲🇾

Hospital Pulau Pinang, Pulau Pinang, Malaysia

and more 24 locations

Treating Paroxysmal Nocturnal Haemoglobinuria Patients With rVA576

Phase 3
Completed
Conditions
Paroxysmal Nocturnal Hemoglobinuria (PNH)
Interventions
Drug: rVA576
Other: Standard of care (SOC)
First Posted Date
2018-07-17
Last Posted Date
2020-11-04
Lead Sponsor
AKARI Therapeutics
Target Recruit Count
9
Registration Number
NCT03588026
Locations
🇱🇰

University of Kelaniya, Faculty of Medicine, Thalagolla Road, Colombo, Sri Lanka

🇰🇿

Almaty City Hospital No.7, Almaty, Microdistrict Kalkaman, Kazakhstan

🇱🇹

Vilnius University Hospital Santaros Klinikos , Santariškių St. 2, LT-08661,, Vilnius, Lithuania

Coversin in Paroxysmal Nocturnal Haemoglobinuria (PNH)

Phase 2
Completed
Conditions
Paroxysmal Nocturnal Haemoglobinuria (PNH)
Interventions
First Posted Date
2015-10-30
Last Posted Date
2023-07-12
Lead Sponsor
AKARI Therapeutics
Target Recruit Count
1
Registration Number
NCT02591862
Locations
🇳🇱

Dr Saskia Langemeijer, Nijmegen, Netherlands

Study of Global Coagulation Tests in Patients With Paroxysmal Nocturnal Haemoglobinuria

Completed
Conditions
Paroxysmal Nocturnal Haemoglobinuria
First Posted Date
2009-11-25
Last Posted Date
2019-09-06
Lead Sponsor
King's College Hospital NHS Trust
Target Recruit Count
60
Registration Number
NCT01020188
Locations
🇬🇧

King's College Hospital NHS Trust, London, United Kingdom

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