Anocca Submits Clinical Trial Application to EMA for ANOC-001 in Advanced Pancreatic Cancer
Anocca has submitted a Clinical Trial Application (CTA) to the EMA for its VIDAR-1 Phase I/II trial.
Metformin Enhances Lung Cancer Immunotherapy in Overweight Patients, Study Finds
A new study suggests metformin, a common diabetes drug, can boost the effectiveness of immunotherapy in lung cancer patients.
MaaT Pharma's MaaT033 Shows Promise in Phase 1b ALS Trial, Eyes Phase 2
MaaT Pharma's Phase 1b trial of MaaT033 in ALS patients met its primary endpoint, demonstrating good safety and tolerability over two months.
DOL Clarifies FMLA Coverage for Clinical Trial Participation
The Department of Labor (DOL) has clarified that participation in a clinical trial can qualify as 'treatment' under the Family and Medical Leave Act (FMLA).
DOL Clarifies FMLA Coverage for Clinical Trial Participation
The Department of Labor (DOL) has clarified that participation in a clinical trial can qualify as 'treatment' under the Family and Medical Leave Act (FMLA).
Oncolytic Virus and Toripalimab Combination Shows Promise in Acral Melanoma
A phase Ib trial of neoadjuvant oncolytic virus OrienX010 combined with toripalimab in resectable acral melanoma (AM) demonstrated a 77.8% pathological response rate.
Poseida's Allogeneic CAR-T Therapy Shows Promise in Relapsed/Refractory Multiple Myeloma
P-BCMA-ALLO1, an allogeneic CAR-T therapy from Poseida Therapeutics, demonstrates promising results in heavily pretreated multiple myeloma patients.
Radiopharmaceutical Developed by PhD Student to Enhance Lung Cancer Immunotherapy Delivery to Brain Metastases
A novel radiopharmaceutical developed by Stephanie Borlase will be used in a clinical trial to track immunotherapy delivery to brain metastases in lung cancer patients.
AXS-05, a Novel NMDA Receptor Antagonist, Shows Promise for Agitation in Alzheimer's Disease
AXS-05, combining dextromethorphan and bupropion, is under development by Axsome Therapeutics for agitation in Alzheimer's disease, offering a novel approach by targeting glutamate and NMDA receptors.
HER2-Targeted Therapies Solidify Role in Early-Stage HER2-Positive Breast Cancer Treatment
Neoadjuvant HER2-targeted therapy, including trastuzumab and pertuzumab, has become a standard of care for stage II/III HER2-positive breast cancer, improving event-free and overall survival.
Neurogene Halts High-Dose Arm of Rett Syndrome Trial After Patient Death
Neurogene's Phase I/II Rett syndrome trial experienced a patient death linked to the higher dose (3E15 vg) of NGN-401 gene therapy, triggering systemic hyperinflammatory syndrome.
Dr. Reddy's Launches Toripalimab in India for Nasopharyngeal Carcinoma Treatment
Dr. Reddy's Laboratories has launched Toripalimab in India, an immuno-oncology drug approved for recurrent or metastatic nasopharyngeal carcinoma (RM-NPC).
TAR-210 Shows Promise in FGFR-Altered Non-Muscle Invasive Bladder Cancer
A phase 1 study evaluates TAR-210, an intravesical formulation of erdafitinib, for high- and intermediate-risk non-muscle invasive bladder cancer (NMIBC).
Vitamin D3 Dosage Trial in Critically Ill Patients Undergoing Continuous Renal Replacement Therapy
A clinical trial is underway to compare the effects of two different doses of vitamin D3 in critically ill patients receiving continuous renal replacement therapy (CRRT).
Ulster University Researchers Discover Novel Protein Markers for Early CKD Diagnosis and COVID-19 Severity Prediction
Researchers at Ulster University have identified protein markers in senescent cells for earlier diagnosis and more effective treatment of Chronic Kidney Disease (CKD).
Wegovy Enters Chinese Market as Obesity Rates Rise
Wegovy, a weight-loss drug containing semaglutide, has been introduced in China, offering a new treatment option for the country's increasing obese population.
MicuRx's MRX-4 Meets Primary Endpoint in Phase III cSSTI Trial
MicuRx's MRX-4 for injection, transitioning to oral Contezolid, demonstrated non-inferiority to intravenous Linezolid in treating complex skin and soft tissue infections (cSSTI).
Peer Education Improves Medication Adherence and Cost-Effectiveness in Elderly Hypertensive Patients
A randomized clinical trial demonstrated that peer-led education significantly improved medication adherence among elderly patients with hypertension.
Elevated Red Cell Distribution Width Linked to Increased Mortality in Sepsis-Associated Liver Injury
A retrospective study of 529 patients with sepsis-associated liver injury (SALI) found that elevated red cell distribution width (RDW) was prevalent in 46.1% of cases.
HepB-CpG Vaccine Shows Superior Response in HIV Patients Non-Responsive to Traditional Hepatitis B Vaccine
A phase 3 trial showed HepB-CpG vaccine achieved superior seroprotection in HIV patients who did not respond to prior HepB-alum vaccination.