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Low Adoption of Proven Neoadjuvant Chemotherapy in Primary Urethral Cancer Raises Treatment Access Concerns

2/21/2025

Despite demonstrating a 7% improvement in 5-year overall survival, neoadjuvant chemotherapy followed by surgery is utilized in only 19% of primary urethral cancer patients.

Innovative Strategies for Patient Recruitment in Rare Disease Trials: Lessons from the Alkaptonuria Experience

2/19/2014

The National Alkaptonuria Centre (NAC) and DevelopAKUre clinical trials face significant recruitment challenges, needing to identify patients from a limited global pool of only 1,000 known cases.

Gender Gap Widens in HIV Life Expectancy: Women Face Significant Disparities Despite Overall Improvements

2/12/2025

A British Columbia study reveals that despite overall improvements in HIV life expectancy from 1996-2020, women consistently lag behind men, with the gender gap increasing to 7.05 years by 2020.

Cost-Effectiveness Analysis Critical for Optimizing CAR-T and Bispecific Therapies in Blood Cancers

2/27/2025

Leading oncologist from City of Hope Cancer Center highlights urgent need for cost-effectiveness studies in hematologic malignancy treatments to optimize healthcare resource utilization.

Osivax Raises €10M in Series B Funding to Advance Broad-Spectrum Influenza Vaccine Development

3/5/2025

Osivax secures €10 million in Series B financing, with strategic investment from Japanese pharmaceutical leader Meiji Seika Pharma, to accelerate development of broad-spectrum influenza vaccine candidates.

Experts Call for Reform in Experimental Treatment Access: Balancing Patient Rights with Sustainable Development

9/17/2022

Leading healthcare experts advocate for a pre-approval access platform to streamline experimental treatment availability while maintaining safety oversight and clinical research integrity.

Sanofi Establishes €66 Million Global R&D Hub in Chengdu, Expanding China Research Footprint

7/2/2018

Sanofi is investing €66 million to establish a new global research hub in Chengdu, China, focusing on data analysis and management of multi-center clinical trials.

BridGene and Takeda Form $770M Alliance to Tackle Undruggable Targets in Neurology and Immunology

2/25/2025

BridGene Biosciences partners with Takeda in a strategic collaboration worth up to $770 million to discover small molecule drugs for challenging immunology and neurology targets using IMTAC™ platform.

TScan Therapeutics Reports Promising Results in Blood Cancer Trial with Only 8% Relapse Rate

3/5/2025

TScan's ALLOHA trial demonstrates significant efficacy with only 2 out of 26 patients experiencing relapse in blood cancer treatment, compared to 33% in the control group.

Global Lung Ambition Alliance Takes Aim at Three Major Challenges in Lung Cancer Care

1/20/2020

The Lung Ambition Alliance, a partnership of major healthcare organizations, aims to double five-year lung cancer survival rates by 2025 through improved screening, innovative medicines, and enhanced quality of care.

Vifor Pharma and Fresenius Kabi Form Strategic Alliance to Address Iron Deficiency in China

2/19/2020

Vifor Pharma and Fresenius Kabi establish a joint venture with 55/45 ownership split to market intravenous iron products across China, targeting over 2,000 tier 3 hospitals.

AstraZeneca and Daiichi Sankyo Partner in $6.9B Deal for Novel HER2-Targeting Cancer Drug

3/28/2019

AstraZeneca commits $3.5 billion upfront and up to $5.55 billion in milestone payments to co-develop trastuzumab deruxtecan, a promising antibody-drug conjugate for HER2-expressing cancers.

NIHR and Pfizer Launch Initiative to Enhance Patient Engagement in UK Clinical Trials Design

11/16/2020

The National Institute for Health Research (NIHR) and Pfizer have established a collaborative framework to facilitate patient engagement in clinical trial design while maintaining compliance with ABPI guidelines.

FDA Approves Zevtera for S. aureus Bacteremia, Marking First New Treatment in 15 Years

3/1/2025

Basilea Pharmaceutica's Zevtera (ceftobiprole) receives FDA approval for three indications, becoming the first beta-lactam antibiotic approved for Staphylococcus aureus bacteremia.

Disease Rarity and Clinical Benefits Drive Rare Disease Drug Pricing in Germany's AMNOG System

2/1/2021

Germany's AMNOG system evaluates rare disease drugs based on multiple factors, with drugs treating ultra-rare conditions generally commanding higher prices while staying below €50 million annual sales threshold.

Addressing the Trust Crisis in Clinical Trials: Lessons from Historical Cases to Modern Solutions

1/26/2021

The COVID-19 pandemic has intensified public scrutiny of clinical trials, revealing widespread misconceptions and distrust in medical research processes and vaccine development.

Breakthrough in Long COVID Detection: Blood Test Could Be Available Within 6-12 Months

7/11/2021

Imperial College London researchers have identified distinctive autoimmune antibodies in long COVID patients' blood, paving the way for a diagnostic test within 6-12 months.

4th RNA-Targeted Drug Discovery Summit to Showcase Latest Advances in Small Molecule Therapeutics

9/27/2021

Leading pharmaceutical companies including Novartis, AstraZeneca, and Roche will present breakthrough developments in RNA-targeted small molecule drug discovery at the December summit.

RSV Emerges as Hidden Threat to Elderly Population, Causing 8,000 Annual Deaths in UK

12/13/2022

Respiratory Syncytial Virus (RSV) significantly impacts older adults, with 79% of adult RSV hospitalizations occurring in those aged 65+ years and causing approximately 8,000 deaths annually in the UK.

Boehringer Ingelheim and Click Therapeutics Expand Digital Therapeutics Alliance for Schizophrenia in $460M Deal

12/19/2022

Boehringer Ingelheim and Click Therapeutics are developing a novel prescription digital therapeutic combining multiple clinically validated interventions for schizophrenia treatment, addressing limited access to psychosocial therapies.

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