MedPath
Found 5 clinical trials|View Analysis
Sort by:

Orelabrutinib in Combination With Thiotepa in Refractory and Relapsed Primary CNS Lymphoma

Phase 1
Conditions
PCNSL
Refractory and Relapsed Primary CNS Lymphoma
Non Hodgkin Lymphoma
Interventions
First Posted Date
2021-08-26
Last Posted Date
2021-08-26
Lead Sponsor
Huiqiang Huang
Target Recruit Count
29
Registration Number
NCT05021770
Locations
🇨🇳

Department of Medical Oncology, Sun Yat-sen University Cancer Center, Guangzhou, Guangdong, China

Immunotherapy Using CAR T-cells to Target CD19 for Relapsed/Refractory CD19+ Primary CNS Lymphoma

Phase 1
Active, not recruiting
Conditions
Primary CNS Lymphoma
Interventions
Biological: CD19CAR T-cells
First Posted Date
2020-06-23
Last Posted Date
2024-05-30
Lead Sponsor
University College, London
Target Recruit Count
12
Registration Number
NCT04443829
Locations
🇬🇧

University College London Hospital, London, United Kingdom

Tisagenlecleucel In Primary CNS Lymphoma

Phase 1
Active, not recruiting
Conditions
Relapsed Primary CNS Lymphoma
Primary CNS Lymphoma
Refractory Primary CNS Lymphoma
Interventions
First Posted Date
2019-10-22
Last Posted Date
2024-04-16
Lead Sponsor
Matthew J. Frigault, M.D.
Target Recruit Count
6
Registration Number
NCT04134117
Locations
🇺🇸

Massachusetts General Hospital, Boston, Massachusetts, United States

Venetoclax and Obinutuzumab for Relapsed/Refractory Primary CNS Lymphoma

Phase 1
Terminated
Conditions
Primary CNS Lymphoma
Interventions
First Posted Date
2019-08-29
Last Posted Date
2022-01-19
Lead Sponsor
Klinikum Stuttgart
Target Recruit Count
4
Registration Number
NCT04073147
Locations
🇩🇪

Klinikum Stuttgart, Stuttgart, Baden-Württemberg, Germany

Rituximab in Treating Patients With Refractory or Relapsed Primary CNS Lymphoma

Phase 2
Terminated
Conditions
Lymphoma
Interventions
Biological: rituximab
First Posted Date
2003-11-06
Last Posted Date
2013-08-28
Lead Sponsor
Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins
Target Recruit Count
12
Registration Number
NCT00072449
Locations
🇺🇸

Winship Cancer Institute of Emory University, Atlanta, Georgia, United States

🇺🇸

Abramson Cancer Center of the University of Pennsylvania, Philadelphia, Pennsylvania, United States

🇺🇸

Massachusetts General Hospital, Boston, Massachusetts, United States

and more 6 locations
© Copyright 2025. All Rights Reserved by MedPath