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Franco-German Project REDUCE-LUNG Aims to Optimize Lung Cancer Treatment in Elderly Patients

11/27/2024

The University Hospital Cologne and Gustave Roussy have launched REDUCE-LUNG, a joint study focused on improving outcomes for lung cancer patients over 70.

Asunercept Shows Promise in Reducing Mortality and Accelerating Recovery in Severe COVID-19

11/14/2024

A Phase 2 clinical trial reveals that asunercept, a FasL inhibitor, significantly accelerates recovery in patients with severe COVID-19, reducing the average recovery time from 13 to 8 days.

MATTERHORN Trial: TEER Non-Inferior to Surgery for Secondary Mitral Regurgitation

9/1/2024

The MATTERHORN trial demonstrated that transcatheter edge-to-edge repair (TEER) is non-inferior to surgery in treating secondary mitral regurgitation (MR) at one year.

AI-Powered Model Aims to Decode Genetic Variants in Stargardt Disease

9/9/2024

Researchers are developing an AI model to classify genetic variants of the ABCA4 gene, crucial for understanding Stargardt disease.

Chemo-Free Triplet Therapy Shows Promise in Richter Transformation

9/16/2024

A phase II trial (MOLTO) found that a chemotherapy-free regimen of atezolizumab, venetoclax, and obinutuzumab yielded a 67.9% overall response rate in patients with Richter transformation.

University of Virginia Expands Manning Institute of Biotechnology with $66M Additional Contract

5/20/2025

Skanska has secured an additional $66 million contract with the University of Virginia to construct the Paul and Diane Manning Institute of Biotechnology, bringing advanced translational research capabilities to the Commonwealth.

Capmatinib Demonstrates Sustained Efficacy in MET Exon 14-Mutated NSCLC

10/15/2024

Final results from the phase II GEOMETRY mono-1 trial reinforce capmatinib's effectiveness in treating NSCLC patients with MET exon 14 skipping mutations.

Cefiderocol Shows Higher Efficacy When Used Earlier in Treatment of Serious Gram-Negative Infections

4/10/2025

New data from the PROVE study reveals cefiderocol achieves better clinical outcomes when used as empiric (64.6%) or documented therapy (67.4%) compared to salvage therapy (58.2%) in serious gram-negative infections.

University of Central Lancashire's Clinical Trials Unit Achieves Full Registration Status

10/16/2024

The Lancashire Clinical Trials Unit (CTU) has been granted full registration status by the UK Clinical Research Collaboration (UKCRC).

NIH Grant Supports Development of Patient-Specific Breast Reconstruction Molds

8/27/2024

A multi-institutional research team secured a $2.7 million NIH grant to develop patient-specific molds for breast reconstruction after mastectomy, aiming to improve efficiency and psychosocial outcomes.

NIH Funds Research to Enhance Precision Probiotic Interventions

11/16/2024

NIH is funding research to develop precision probiotic interventions that account for human heterogeneity, aiming to improve therapeutic responses.

University of Birmingham Pioneers Personalized Cancer Treatment Approaches with Novel Technologies

2/4/2025

University of Birmingham researchers are revolutionizing cancer diagnosis through innovative MRI and machine learning techniques that can identify pediatric brain tumor types in just ten minutes.

AbbVie's Vyalev for Parkinson's Disease Incorporates Key Innovations from KU Chemist

12/17/2024

Vyalev, a new subcutaneous drug therapy by AbbVie for Parkinson's disease, has been approved by the FDA in October 2024 after successful Phase 3 trials.

Hyperbaric Oxygen Therapy Evaluated for Ulcerative Colitis Treatment in Clinical Trial

9/10/2024

A clinical trial is underway at the University of Miami Miller School of Medicine, among 15 sites, to assess hyperbaric oxygen therapy (HBOT) for ulcerative colitis treatment.

ARPA-H Funds Multi-Institutional Consortium to Cure Blindness Through Eye Transplantation

12/2/2024

The University of Colorado Anschutz Medical Campus will receive up to $46 million from ARPA-H to advance vision-restoring human whole eye transplantation.

McMaster University Launches Phase-2 Trial of Novel Inhaled COVID-19 Vaccine

3/10/2025

Canadian researchers at McMaster University have begun phase-2 clinical trials for AeroVax, an innovative inhaled COVID-19 vaccine that directly targets the lungs and upper airways where infection begins.

University of Alberta's Novel Cancer Drug Zelenirstat Receives FDA Fast-Track Designation

2/12/2025

University of Alberta researchers have developed Zelenirstat, an innovative oral cancer medication that works by preventing cancer cell spread and starving tumors.

University of Montana's Cancer Immunotherapy Enters Phase 1 Human Trials

9/5/2024

Researchers at the University of Montana, in partnership with Inimmune, have advanced a novel cancer treatment into Phase 1 human clinical trials.

University of Pittsburgh Develops 100-Biomarker Blood Test for Alzheimer's Disease

11/4/2024

Researchers at the University of Pittsburgh have validated a blood test that measures over 100 genetic sequences associated with Alzheimer's disease, potentially replacing spinal taps.

Ketamine vs. Fentanyl: Utah Study Aims to Reshape Prehospital Pain Management

8/28/2024

A clinical trial is underway to compare ketamine and fentanyl for prehospital pain management in trauma patients.

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