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Drone Technology Trials Begin for Rapid Delivery of Radioactive Medicines in Coventry

3/27/2025

Coventry-based Skyfarer has partnered with University Hospitals Coventry and Warwickshire NHS Trust to test drone delivery of radioactive medicines, potentially reducing transport time significantly.

Osivax Initiates Phase 2a Booster Trial of Broad-Spectrum Influenza Vaccine OVX836

11/16/2024

Osivax has dosed the first participant in a Phase 2a clinical trial evaluating OVX836 as a booster for its broad-spectrum influenza vaccine candidate.

Study Calls for Optimization of High-Cost IVIG Therapy in BK Nephropathy Treatment

12/24/2024

Research from the Medical University of South Carolina indicates that single-dose IVIG therapy (2g/kg) may be sufficient for clearing BK viral load in nephropathy patients, potentially reducing overall treatment costs.

Home Administration of Long-Acting HIV Injectable Therapy Proves Safe and Effective as Clinic Treatment

5/4/2025

A study by the Medical University of South Carolina demonstrates that home administration of long-acting injectable antiretroviral therapy (ART) for HIV patients is as safe and effective as clinic-based administration.

Clear Roads Initiative Drives Innovation in Winter Road Maintenance

12/6/2024

The Clear Roads research program unites transportation experts nationwide to advance winter maintenance strategies.

EMA Recommends Non-Renewal of Translarna for Duchenne Muscular Dystrophy

6/28/2024

The EMA's CHMP has recommended not renewing the marketing authorization for Translarna (ataluren) for Duchenne muscular dystrophy patients with nonsense mutations.

Jennifer Jao Appointed Co-Chair of IMPAACT Network to Advance Pediatric HIV Clinical Trials

1/13/2025

Dr. Jennifer Jao of Northwestern University will co-chair the International Maternal Pediatric and Adolescent AIDS Clinical Trials (IMPAACT) Network.

FDA Approval of Humacyte's Artificial Blood Vessel Faces Petition for Revocation Amid Safety Concerns

3/25/2025

Northeastern University researchers have formally petitioned the FDA to revoke approval of Humacyte's artificial blood vessel Symvess, citing deficient clinical trial data and safety concerns.

Study Links Semaglutide to Increased Risk of Vision-Threatening Eye Condition

2/20/2025

New research from Johns Hopkins University reveals that semaglutide (Ozempic, Wegovy) is associated with a 32% increased relative risk of nonarteritic anterior ischemic optic neuropathy, a potentially blinding eye condition.

Brisk Walking Significantly Reduces Risk of Heart Rhythm Disorders, New Study Finds

4/17/2025

Research published in the journal Heart reveals that individuals who walk at a brisk pace (over 4 mph) have a 43% lower risk of developing abnormal heart rhythms compared to slower walkers.

UHNM Recognized for Leading Role in National Stroke Trials

1/15/2025

The University Hospitals of North Midlands NHS Trust (UHNM) has been acknowledged as a top recruiter of patients for two significant national clinical trials on stroke treatment, ATTEST 2 and OPTIMAS, with findings published in the Lancet and presented at the World Stroke Congress 2024.

Implantable Biobattery Achieves 99.6% Tumor Reduction in Breakthrough Drug-Free Cancer Treatment

5/29/2025

A novel implantable biobattery developed by researchers at University of Wollongong and Jilin University reduced tumor size from over 1,000 mm³ to just 4 mm³ in 14 days, achieving a 99.6% reduction.

Evolution of Precision Medicine Reshapes Cancer Treatment Landscape, Expert Highlights Future of Blood-Based Monitoring

10/30/2024

Precision medicine in oncology has evolved from early hormone-based treatments to sophisticated molecular targeting, revolutionizing treatment approaches for diseases like breast cancer and CML.

Study Reveals Lack of Clinical Validation for Nearly Half of FDA-Authorized AI Medical Devices

10/2/2024

A recent study in _Nature Medicine_ found that 43% of FDA-authorized AI medical devices lack publicly available clinical validation data, raising concerns about their effectiveness.

Agios Completes Enrollment of Phase 3 RISE UP Study of Mitapivat in Sickle Cell Disease

10/23/2024

Agios Pharmaceuticals has completed enrollment for the Phase 3 RISE UP study evaluating mitapivat in sickle cell disease patients aged 16 and older.

Concussions in Hockey Players Linked to Doubled Risk of Depression and Tripled Risk of Burnout

4/17/2025

Hockey players who suffered three or more concussions had twice the risk of depression symptoms compared to those without concussion history, according to new Swedish research.

Luspatercept Improves Quality of Life in First-Line Treatment of Anemia in Lower-Risk MDS

10/29/2024

Luspatercept's approval offers an effective and well-tolerated first-line treatment for anemia in lower-risk myelodysplastic syndrome (MDS) patients without prior ESA use.

Caribou Biosciences Expands Clinical Development of CB-010 with FDA Clearance of IND in Lupus

4/4/2024

Caribou Biosciences has received FDA clearance for its IND application for CB-010, an allogeneic anti-CD19 CAR-T cell therapy, to treat lupus nephritis and extrarenal lupus. The GALLOP Phase 1 clinical trial is set to begin by the end of 2024, following encouraging results from the ANTLER trial for B cell non-Hodgkin lymphoma.

Fedratinib for the Treatment of Myelofibrosis: A Review of Clinical Trial and Real-World Data

1/14/2025

This article reviews the efficacy and safety of fedratinib in treating myelofibrosis, based on clinical trial data and real-world evidence. It highlights the drug's impact on spleen volume response, symptom improvement, and adverse effects, including gastrointestinal issues and hematologic toxicities.

First Human Transplant of Sperm-Producing Stem Cells Offers Hope for Childhood Cancer Survivors

3/28/2025

A 26-year-old bone cancer survivor has received the first known transplant of sperm-producing stem cells preserved from his childhood, marking a significant advancement in fertility preservation for pediatric cancer patients.

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