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Low-Dose Aspirin Evaluated for Gastric Cancer Prevention in High-Risk Iranian Population

9/19/2024

A phase III randomized controlled trial is underway in Iran to assess the effectiveness of long-term, low-dose aspirin in preventing gastric cancer.

Spine BioPharma Completes Enrollment in Phase 3 Trial of SB-01 for Chronic Low Back Pain

9/25/2024

Spine BioPharma completed enrollment in its Phase 3 MODEL trial, evaluating SB-01 for chronic low back pain (CLBP) due to degenerative disc disease (DDD).

Anakinra Shows Promise in Reducing Endometriosis-Related Pain and Inflammation in Pilot Study

9/27/2024

A pilot study suggests that anakinra, an IL-1 antagonist, may reduce dysmenorrhea pain scores in women with endometriosis.

Combination Therapy Shows Promise in Oligometastatic Prostate Cancer

9/29/2024

A phase 2 trial (SHARP) indicates that combining radium-223 dichloride with stereotactic body radiation therapy (SBRT) and ADT is well-tolerated for mCSPC.

Puma Biotechnology Initiates Phase II Trial of Alisertib for HR+/HER2- Metastatic Breast Cancer

11/20/2024

Puma Biotechnology has commenced the ALISCA™-Breast1 Phase II trial to evaluate alisertib combined with endocrine therapy for HR+/HER2- metastatic breast cancer.

Palatin Technologies Advances PL8177 for Ulcerative Colitis and Bremelanotide for Obesity

11/25/2024

Palatin Technologies has completed enrollment in its Phase 2 study of oral PL8177 for ulcerative colitis, with topline data expected in Q1 2025.

Puma Biotechnology Initiates Phase II Trial of Alisertib for HR+/HER2- Metastatic Breast Cancer

11/20/2024

Puma Biotechnology has commenced the ALISCA™-Breast1 Phase II trial to evaluate alisertib combined with endocrine therapy for HR+/HER2- metastatic breast cancer.

Vitamin D3 Dosage Trial in Critically Ill Patients Undergoing Continuous Renal Replacement Therapy

11/24/2024

A clinical trial is underway to compare the effects of two different doses of vitamin D3 in critically ill patients receiving continuous renal replacement therapy (CRRT).

Delcath's Hepzato Kit Trials in Liver-Dominant Metastatic Colorectal Cancer Following FDA Clearance

12/2/2024

Delcath Systems received FDA clearance for its IND application to initiate a Phase 2 trial of Hepzato Kit in liver-dominant metastatic colorectal cancer (mCRC).

Mesoglycan Evaluated for Hemorrhoidal Disease in CHORMES Trial

12/2/2024

The CHORMES study is a randomized, double-blind, placebo-controlled trial investigating mesoglycan for treating acute hemorrhoidal disease (HD).

Cytokinetics Initiates Phase 3 COMET-HF Trial of Omecamtiv Mecarbil for Severe Heart Failure

12/4/2024

Cytokinetics has commenced the COMET-HF trial, a Phase 3 study evaluating omecamtiv mecarbil in patients with symptomatic heart failure and severely reduced ejection fraction.

Belzutifan Monotherapy Shows Manageable Safety Profile in Renal Cell Carcinoma: Pooled Analysis

12/5/2024

A pooled analysis of four clinical trials (n=576) evaluated the safety of belzutifan monotherapy in patients with renal cell carcinoma (RCC).

Imeglimin's Metabolic Action Investigated in New Study Using Advanced Glucose Clamp Technology

10/1/2024

A study investigates imeglimin's impact on metabolic function using a two-step hyperinsulinemic-euglycemic glucose clamp, employing an artificial endocrine pancreas to maintain glucose levels.

Insilico Medicine Named a Fierce 50 Honoree for AI-Driven Drug Discovery

10/2/2024

Insilico Medicine has been recognized as a Fierce 50 honoree for its pioneering work in AI-driven drug discovery and development.

FDA Authorizes First Over-the-Counter Combination Flu and COVID-19 Test

10/8/2024

The FDA has granted De Novo marketing authorization to Healgen Scientific for its Rapid Check COVID-19/Flu A&B Antigen Test, the first OTC combination test.

Kineta Completes Enrollment in Monotherapy Arm of VISTA-101 Trial for Advanced Solid Tumors

10/9/2024

Kineta has finished enrolling patients in the monotherapy phase of its Phase 1 VISTA-101 trial, which assesses KVA12123 in advanced solid tumors.

mHealth Intervention Improves Mental Health in Thyroid Cancer Patients

10/15/2024

A mobile health (mHealth) intervention based on the Multi-Theory Model (MTM) significantly reduced anxiety and depression in patients with differentiated thyroid cancer (DTC).

Nurix Therapeutics Appoints Anil Kapur to Board, Plans Pivotal Trial for NX-5948

10/16/2024

Nurix Therapeutics has appointed Anil Kapur, a seasoned pharmaceutical executive, to its board of directors, effective October 15, 2024.

Epcoritamab Approved by FDA for Relapsed/Refractory Follicular Lymphoma

10/17/2024

The FDA has granted accelerated approval to epcoritamab for relapsed or refractory follicular lymphoma after two or more lines of systemic therapy.

Enhanced Donanemab Titration Reduces ARIA-E Risk in Alzheimer's Patients

10/30/2024

A new enhanced titration dosing regimen of donanemab significantly reduced the frequency and severity of amyloid-related imaging abnormalities-edema (ARIA-E).

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