PolTREG Advances CAR-Treg Therapy for Neuroinflammatory Diseases
PolTREG initiates preclinical study of CAR-Treg cells for neuroinflammatory diseases, including multiple sclerosis (MS) and amyotrophic lateral sclerosis (ALS).
Stress Directly Triggers Psoriasis Relapse, Study Confirms
A new study confirms that perceived stress directly triggers psoriasis relapse, providing the first scientific validation of this long-suspected connection.
The Alarm's Mike Peters Achieves Remission from Richter's Syndrome Through NHS Drug Trial
Mike Peters, frontman of The Alarm, achieved remission from aggressive Richter's syndrome after participating in an NHS drug trial at The Christie in Manchester.
Alzheimer's Patient Finds Hope and Purpose Through Clinical Trial Participation
Bob Ehlers, diagnosed with mild cognitive impairment from Alzheimer's, participates in a clinical trial at Banner Alzheimer's Institute to combat disease progression.
Allogene Therapeutics Halts Enrollment in Leukemia Trial Cema-Cel Due to Slow Recruitment
Allogene Therapeutics stopped enrolling patients in its Phase 1 trial of cemacabtagene ansegedleucel (cema-cel) for relapsed or refractory chronic lymphocytic leukemia (CLL).
Tovorafenib Shows Durable Off-Treatment Responses in Pediatric BRAF-Altered Low-Grade Glioma
Tovorafenib (Ojemda) demonstrates durable responses in pediatric patients with BRAF-altered relapsed/refractory low-grade glioma during drug holidays in the FIREFLY-1 trial.
Larimar Therapeutics' Nomlabofusp Shows Promise in Friedreich's Ataxia Studies
Nomlabofusp treatment demonstrates modification of gene expression and lipid profiles, alongside increased frataxin (FXN) levels in Friedreich's ataxia (FA) patients.
Advances in Alzheimer's Diagnostics and Therapeutics Highlighted at Recent Conference
Plasma p-tau217-based tests are seeking regulatory approval in the U.S. and Europe as fully automated in vitro diagnostics for Alzheimer's disease.
Cassava Sciences Bolsters Commercial Strategy with Freda Nassif as Chief Commercial Officer
Cassava Sciences appointed Freda Nassif as Chief Commercial Officer to spearhead commercial strategies for simufilam, their Alzheimer's drug candidate.
Alkeus Pharmaceuticals' Gildeuretinol Receives FDA Fast Track and Rare Pediatric Disease Designations for Stargardt Disease
Gildeuretinol (ALK-001) receives Rare Pediatric Disease and Fast Track designations from the FDA, highlighting the urgent need for Stargardt disease treatments.
CRISPR Therapeutics Faces Slow Casgevy Launch Despite Regulatory Approvals
CRISPR Therapeutics' stock has declined despite the FDA and EU approvals of Casgevy for sickle cell disease and transfusion-dependent beta thalassemia.
Jacobio Pharmaceuticals Initiates Clinical Trial for Novel Cancer Drug
Jacobio Pharmaceuticals has commenced a clinical trial for a new cancer drug, marking a significant step in their oncology program.
FDA Approves BridgeBio's Attruby (acoramidis) for Transthyretin Amyloid Cardiomyopathy
The FDA has approved BridgeBio's Attruby (acoramidis) for adults with transthyretin amyloid cardiomyopathy (ATTR-CM), a rare and life-threatening heart condition.
SynAct Pharma's Resomelagon Receives EU Trial Approval for Phase 2b Rheumatoid Arthritis Study
SynAct Pharma received EU approval for its Phase 2b ADVANCE study of resomelagon (AP1189) in newly diagnosed severe rheumatoid arthritis (RA) patients.
Trikafta Expansion Celebrated as Major Breakthrough for Cystic Fibrosis Patients
Trikafta's expanded coverage marks a significant advancement in treating cystic fibrosis, offering hope for improved outcomes for a broader range of patients.
Cell and Gene Therapy Trials Surge Globally, Led by Oncology and Asia-Pacific Region
Global clinical trials for cell and gene therapies have expanded by 32.5% between 2019 and 2023, indicating rapid growth in the field.
SELLAS' SLS009 Shows Promise in ASXL1-Mutated Solid Cancers
SELLAS Life Sciences reports that SLS009, a CDK9 inhibitor, demonstrates high efficacy in preclinical models of solid cancers with ASXL1 mutations.
Neurologist Diagnosed with Alzheimer's Shares Insights on Disease Management and Research
Dr. Daniel Gibbs, a neurologist with early-stage Alzheimer's, shares his experiences and strategies for slowing disease progression, including diet and exercise.
Sunshine Biopharma's K1.1 mRNA Shows Promise in Treating Liver Cancer in Preclinical Studies
Sunshine Biopharma's K1.1 mRNA demonstrated dose-dependent anti-proliferative activity against human hepatocellular carcinoma (HCC) cells in vitro.
Dermata Therapeutics' DMT310 Nears Phase III Acne Trial Results
Dermata Therapeutics' DMT310, a novel topical product, is in Phase III trials for moderate-to-severe acne, offering a once-weekly treatment option.