Comparing the Effects of Music vs. Non-Music Based Interventions on Auditory and Cognitive Processing in Older Adults
试验速览
- 阶段
- 不适用
- 状态
- 招募中
- 入组人数
- 216
- 试验地点
- 1
- 主要终点
- Digits-in-Noise Task
研究概览
简要总结
The proposed study will enroll healthy older adult participants to examine the effectiveness of music listening activities to promote hearing and cognition. Participants will be randomized into one of four experimental groups and can expect to participate for up to 21 hours of research distributed over 20 weeks.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Basic Science
- 盲法
- Double (Participant, Outcomes Assessor)
入排标准
- 年龄范围
- 60 Years 至 101 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •No self-reported auditory difficulties and normal or near-normal hearing sensitivity as measured by SRTs.
- •Should have no more than typical hearing loss for their age and no evidence of dementia.
- •Fluent in English and/or Spanish
- •No more than two years of formal music training in childhood OR in the past 20 years
排除标准
- •Abnormal vision or hearing prohibitive of training
- •History of seizures, focal brain lesion, or head injury with loss of consciousness
- •Physical handicap (motor or perceptual) that would impede training procedures
- •Social, educational or economic hardship prohibitive to training schedule Concurrent enrollment in other cognitive training studies
- •History of major psychiatric illness, including psychosis, bipolar disorder, depression, alcohol or substance abuse, recent bereavement
- •Geriatric Depression Scale-15 (GDS-15) score of 6 or higher, indicating clinically significant depressive symptoms
- •Not being proficient enough in English or Spanish that would prevent following and understanding all instructions and completing all testing sessions
- •Diagnosis of dementia or other neurological disease, including mild cognitive impairment (MCI)
- •Telephone-Montreal Cognitive Assessment (t-MoCA) score of 16 or less
结局指标
主要结局
Digits-in-Noise Task
时间窗: Pre-test (week 1), Mid-test (week 5), Post-test (week 10), Follow-up (week 18)
The Digits-in-Noise (DIN) test presents trials of three sequential spoken digits against a broad-band, speech-shaped masker. Signal/noise ratio is varied adaptively to track 50% correct. The dependent variable is the threshold noise tolerance in dB. Lower scores indicate better performance.
Spatial Release From Masking Task
时间窗: Pre-test (week 1), Mid-test (week 5), Post-test (week 10), Follow-up (week 18)
Tests the ability to distinguish speech from competing speech. Collocated condition uses target and two competing maskers all located directly in front of the listener, and spatially separated condition uses two masking sentences sent from 45 degrees to the left and right of center. Sentences are correctly identified as part of a series of test trials in which TMR progressively reduced every two trials. The dependent variable is the threshold target-to-masker ratio (TMR) as estimated based on the number of sentences correctly identified. Lower scores indicate better performance.
Dichotic Sentence Identification Task
时间窗: Pre-test (week 1), Mid-test (week 5), Post-test (week 10), Follow-up (week 18)
The DSI test simultaneously presents two nonsense sentences, one to each ear. Participants indicate two sentences heard from a list of alternatives. DSI sentences are presented at a comfortable listening level, usually 50 dB above pure-tone average of each ear. The dependent variable is the percentage of sentences correctly identified. Higher scores indicate better performance.
次要结局
- Revised Hearing Handicap Inventory for the Elderly (RHHI)(Pre-test (week 1), Post-test (week 10), Follow-up (week 18))
- Speech Recognition Threshold using Coordinate Response Measure(Pre-test (week 1), Mid-test (week 5), Post-test (week 10), Follow-up (week 18))
- Gap Detection Task(Pre-test (week 1), Post-test (week 10))
- Spectrotemporal Sensitivity Task(Pre-test (week 1), Post-test (week 10))
- Monaural and Binaural Sensitivity to Frequency Modulation Task(Pre-test (week 1), Post-test (week 10))
- Audio Visual Divided Attention Task(Pre-test (week 1), Mid-test (week 5), Post-test (week 10), Follow-up (week 18))
- Paced Serial Addition Task(Pre-test (week 1), Post-test (week 10), Follow-up (week 18))
- Letter-Number Sequencing Task(Pre-test (week 1), Post-test (week 10), Follow-up (week 18))
- Auditory N-back Task(Pre-test (week 1), Post-test (week 10), Follow-up (week 18))
研究者
Susanne Jaeggi
Professor of Psychology, Applied Psychology, Music
Northeastern University