跳至主要内容
临床试验/NCT06750328
NCT06750328尚未招募不适用

Procedural and Clinical Outcomes of Isolated Left Circumflex Coronary Artery Acute Occlusion in Patients Undergoing Primary Percutaneous Coronary Intervention

Assiut University0 个研究点目标入组 50 人开始时间: 2024年12月16日最近更新:
适应症

试验速览

阶段
不适用
状态
尚未招募
入组人数
50
主要终点
Complications of PPCI to LCx occlusion

研究概览

简要总结

To assess procedural success and short term clinical outcomes of primary PCI to isolated LCx acute occlusion.

详细描述

ST-segment elevation myocardial infarction (STEMI) involving acute occlusion of the left circumflex (LCx) coronary artery represent only 14-21% of STEMIs

LCx acute occlusion may be difficult to be diagnosed . Only 50% of patients with LCx occlusion exhibited ST segment elevation during the acute phase, 38% showed no ST segment changes, while 15% presented with isolated ST segment depression This may lead to delay in transfer to cath lab, delay in reperfusion therapy and consequently loss of more myocytes and more major adverse cardiovascular events (MACE) .

Due to relative rare occurrence of isolated LCx coronary artery occlusion, little is known in literature about the clinical outcomes of isolated LCx occlusion , so we will conduct a retrospective observational study in our tertiary primary percutaneous coronary intervention (PCI) center to detect the incidence , procedural and clinical outcomes after 6 months of patients who had isolated LCx acute occlusion and underwent primary PCI.

研究设计

研究类型
Observational
观察模型
Cohort
时间视角
Retrospective

入排标准

性别
All
接受健康志愿者

入选标准

  • Patients presented to Assiut University heart hospital with STEMI who underwent primary PCI that revealed isolated LCx acute occlusion (single culprit artery) between January 2018 to January 2025 will be included.

排除标准

  • Patients with cardiogenic shock, NYHA class III-IV and multivessel coronary artery disease will be excluded.

结局指标

主要结局

Complications of PPCI to LCx occlusion

时间窗: 6 months

defined as angiographic success without in-hospital complications). Angiographic success (defined as in-stent residual stenosis ≤30% without serious angiographic complications (severe coronary dissection impairing flow \[type D-F\], perforation, abrupt closure or no reflow) .

次要结局

  • Long follow up of outcomes of PPCI of LCx outcomes(6 months)

研究者

申办方类型
Other
责任方
Principal Investigator
主要研究者

Esraa gamal mohammed

Resident doctor

Assiut University

相似试验