NCT07258823尚未招募不适用
Study on the Effectiveness of Continuous Compression-synchronous Ventilation (Bio-CPR) in the ACLS Stage of Cardiopulmonary Resuscitation (ACLS) Based on the Bionic Concept to Explore the Best Mechanical Ventilation Strategy
适应症
试验速览
- 阶段
- 不适用
- 状态
- 尚未招募
- 入组人数
- 408
- 主要终点
- Mean tidal volume
研究概览
简要总结
Bio-CPR is an innovative new mechanical resuscitation model proposed by our research group. A multi-center RCT study was established to comprehensively evaluate the efficacy of this model and the current standard CPR protocol, verify its safety and efficacy, and provide high-quality clinical evidence support.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- Single (Participant)
入排标准
- 年龄范围
- 18 Years 至 75 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •18-65 years old;
- •Cardiac arrest with witnesses;
- •Onset - compression start time<5 minutes;
- •Initial ventricular fibrillation rhythm;
- •Endotracheal intubation and use of a mechanical chest CPR device; Patients with OHCA who meet the above conditions
排除标准
- •1. OHCA patients who are not suitable for mechanical compression ventilation;
- •The participant or his/her legally authorized representative (LAR) is unable or unwilling to provide written informed consent.
结局指标
主要结局
Mean tidal volume
时间窗: 15 minutes
Mean tidal volume
次要结局
- Mean minute ventilation and end-tidal carbon dioxide(15 minutes)
研究者
lixin
Vice President
Guangdong Provincial People's Hospital
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