Open Lung Approach During General Anaesthesia to Prevent Post-Operative Pulmonary Complications
试验速览
- 阶段
- 不适用
- 发起方
- 试验地点
- 2
研究概览
简要总结
The hypothesis of this study is that the "Open lung approach" ( recruitment and PEEP) during general anaesthesia reduces atelectasis formation and improves respiratory function in the immediate post-operative period after major abdominal surgery.
This is a prospective, randomized, controlled clinical-trial,performed in patients undergoing major abdominal surgery, to compare the effects on the post-operative pulmonary complications of two different intraoperative ventilatory strategies during general anaesthesia: 1- Control Group: PEEP 0 cmH2O without recruitment manoeuvre; 2- Treatment Group:recruitment manoeuvre (after intubation and before extubation) and PEEP 10 cmH2O In the post-operative period the following variables will be recorded at the first, third and fifth postoperative day: 1- Gas-exchange in air; 2- Chest X-ray for atelectasis evaluation; 3- signs of pulmonary complication (cough, secretions, dyspnea, thoracic pain)
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- None
入排标准
- 年龄范围
- 18 Years 至 —(Adult, Older Adult)
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Patients with ASA 1, 2 and 3
- •Age higher than 18 years
- •Major abdominal surgery
- •General anesthesia
排除标准
- •COPD with FEV1 lower than 50%
- •Ischemic cardiopathy
- •Loco-regional anesthesia alone
- •Minor abdominal surgery
- •Laparoscopic surgery
