CTRI/2025/07/090660已完成不适用
Evaluating the role of salivary miRNA 372 and 486-3p as diagnostic biomarkers in Oral Squamous Cell Carcinoma, precancerous lesions and healthy individuals using qRT-PCR.
未提供1 个研究点 分布在 1 个国家目标入组 80 人开始时间: 2025年7月22日最近更新:
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 80
- 试验地点
- 1
- 主要终点
- Identifying biomarkers to understand disease progression
研究概览
简要总结
A double-blind clinical trial has been completed to detect oral premalignancies and cancer at an early stage. The chosen biomarkers for this study were microRNA 372 and 486-3p. Patients who come for routine dental checkups were screened for intra-oral lesions, and saliva samples were collected from them. This study was designed with a sample size of 80, with 20 patients each in Oral cancer, Oral submucous fibrosis, Leukoplakia and controls.
研究设计
- 研究类型
- Observational
入排标准
- 年龄范围
- 21.00 Year(s) 至 71.00 Year(s)（—）
- 性别
- All
入选标准
- •Intra-oral lesion or restricted mouth opening Or suspected oral malignancy.
排除标准
- •Those who are unwilling to participate in study Those with other types of cancers.
结局指标
主要结局
Identifying biomarkers to understand disease progression
时间窗: 3 years down the line
次要结局
- Biomarker based early detection in oral cavity(3 years down the line)
研究者
Dr.M.Parasakthi
SRM Dental College
研究点 (1)
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