Platelet-to-Lymphocyte Ratio and Neutrophil-to-Lymphocyte Ratio in Patients With Helicobacter Pylori-Associated Gastritis
试验速览
- 阶段
- 不适用
- 状态
- 尚未招募
- 入组人数
- 90
- 主要终点
- Neutrophil-to-lymphocyte ratio (NLR) in H. pylori-associated gastritis
研究概览
简要总结
This cross-sectional study aims to evaluate the role of neutrophil-to-lymphocyte ratio (NLR) and platelet-to-lymphocyte ratio (PLR) as inflammatory markers in patients with Helicobacter pylori-associated gastritis at Assiut University Hospitals.
详细描述
Helicobacter pylori is a major cause of gastritis and is associated with chronic gastric inflammation. Systemic inflammatory markers derived from complete blood count, such as the neutrophil-to-lymphocyte ratio (NLR) and platelet-to-lymphocyte ratio (PLR), have been proposed as simple and inexpensive indicators of inflammation.
This cross-sectional study will include adult patients with dyspepsia undergoing testing for H. pylori by endoscopy and biopsy at Assiut University Hospitals. Complete blood count will be performed to calculate NLR and PLR. The study will assess the association of these ratios with the presence of H. pylori infection and the severity of gastritis.
研究设计
- 研究类型
- Observational
- 观察模型
- Case Only
- 时间视角
- Cross Sectional
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •- Age 18 years or older
- •Patients with dyspepsia
- •Patients undergoing endoscopy and biopsy for H. pylori testing
- •Willingness to provide informed consent
排除标准
- •- Hematological diseases
- •Active infection other than H. pylori
- •Chronic inflammatory or autoimmune diseases
- •Malignancy
- •Recent use of steroids or immunosuppressive drugs
- •Recent acute bleeding
结局指标
主要结局
Neutrophil-to-lymphocyte ratio (NLR) in H. pylori-associated gastritis
时间窗: Baseline
Neutrophil-to-lymphocyte ratio calculated from complete blood count in patients with confirmed H. pylori-associated gastritis compared with patients without H. pylori infection.
次要结局
- Platelet-to-lymphocyte ratio (PLR)(Baseline)
- Diagnostic performance of NLR(Baseline)
- Diagnostic performance of PLR(Baseline)
- Association with severity of gastritis(Baseline)
- Correlation of NLR and PLR with severity of gastritis(Baseline)
研究者
Hadeer Abdelaal Mohamed Mohamed
Resident Physician, Department of Internal Medicine
Assiut University