Feasibility and Preliminary Data on the Interplay Between Oxytocin and Cortisol During Stress in Borderline Personality Disorder
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 100
- 试验地点
- 1
- 主要终点
- Salivary cortisol
研究概览
简要总结
This study aims to determine the feasibility and preliminary data on the interaction between oxytocin and cortisol during stress in borderline personnality disorder.
详细描述
The investigators will recruit 50 female patients with borderline personnality disorder and 50 controls with no psychiatric diagnosis, aged between 18 and 25 years old.
salivary cortisol daily curve ( 6 measures during the day) will be measured in participant's naturalistic environnement, together with salivary oxytocin. In addition, salivary oxytocin and cortisol will be measured during a psychosocial stress task and recovery.
研究设计
- 研究类型
- Observational
- 观察模型
- Case Control
- 时间视角
- Prospective
入排标准
- 年龄范围
- 18 Years 至 35 Years（Adult）
- 性别
- Female
- 接受健康志愿者
- 是
入选标准
- •Borderline personality disorder-DSM V
排除标准
- •Schizophrenia
结局指标
主要结局
Salivary cortisol
时间窗: Change during experimental task (up to 2 hours)
salivary cortisol measured with salivettes (swabs)
Salivary oxytocin
时间窗: Change during experimental task (up to 2 hours)
salivary oxytocin measured with salivettes (swabs)
次要结局
未报告次要终点
研究者
Tatiana Aboulafia Brakha
PhD
University of Geneva, Switzerland