Comparison of Buccal Midazolam Versus Inter-muscular Midazolam in Control of Seizures
试验速览
- 阶段
- 4 期
- 状态
- 已完成
- 发起方
- 入组人数
- 90
- 试验地点
- 1
研究概览
简要总结
The goal of this clinical trial(Quasi Experimental) is to compare efficacy of oral midazolam over intra-muscular Midazolam in children suffering from seizures. The main question it aims to answer is:
Does Buccal midazolam has a better efficacy as compared to intramuscular midazolam in children presenting with seizures?
There will be two groups determined by randomisation and then one will be given buccal midazolam and other will will be administered IM Midazolam .The out come will be determined by the determining the cessation of seizures within 5 minutes duration achieved by administration of drug.
详细描述
Introduction:
Generalised convulsive seizure is a serious and potentially life threatening medical emergency that requires prompt intervention. Administration of buccal midazolam is an efficient and easier method for control of seizures without the need for intravenous cannulation expertise or intramuscular injections.
Objectives:
To compare the outcome of buccal midazolam versus intramuscular midazolam in children presenting with seizures.
Study Design: Quasi experimental study
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- Single (Participant)
入排标准
- 年龄范围
- 6 Months 至 12 Years（Child）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Children of age 6 months to 12 years, both genders, presenting with seizures (as per operational definition)
- •Children with Seizure disorder, Febrile fits, Meningitis without raised intracranial pressure.
排除标准
- •Children with cardiac arrest or hemodynamic instability at presentation, head trauma or drowning.
- •Diagnosed cases of metabolic disorders, CKD.
- •Diagnosed case of raised ICP.
研究者
Muhammad Tayyab Qureshi
Dr
Pakistan Air Force (PAF) Hospital Islamabad