jRCTs021190008已完成不适用
Integrative aging control intervention trial for age-related cognitive decline (Anti-aging trial)
未提供0 个研究点目标入组 60 人开始时间: 待定最近更新:
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 60
- 主要终点
- Transiton of Memory performance index score
研究概览
简要总结
暂无简介。
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized Controlled Trial
- 干预模型
- Parallel Assignment
- 主要目的
- Prevention Purpose
- 盲法
- Double Blind
入排标准
- 年龄范围
- 60age old over 至 No limit（—）
- 性别
- All
入选标准
- •Those who fell under the following screening criteria and are suspected of having memory impairment in the memory examination of the Iwaki Health Promotion Project Medical Checkup in 2014-
- •Some of the above were susequently diagnosed as having mild cognitive impairment by the detailed health checkup in Univeristy hospital.
- •Screening criteria-
- •Subjects who satisfied all following 1-3 criteria
- •cognitive dysfunction recognized by both the subject or its family
- •delay playback score are less than 2 points in MMSE problem 5
- •WMS-R Logical Memory Test II meets the following criteria
- •/8 points or less for the subject with 16 years of education/ 4 points or less for the subject with 10-15 years of education/ 2 points or less for the subject 9 years or less
排除标准
- •Those who suffer from severe lovel of cancer, diabetes, high blood pressure or etc.
- •Those who are taking cholin esterase inhibitors (only for the treatment of dementia)
- •Those who are allergic to the ingredients contained in the test supplement
- •Those who suffer from psychosis or express psychiatric symptoms
- •Those who suffer from dementia.
结局指标
主要结局
Transiton of Memory performance index score
时间窗: three months, six months, 1.5 years, 2.5 years and 3.5 years
from the start of the test to the end (three months, six months, 1.5 years, 2.5 years and 3.5 years after the start of the test)
Change of memory performance index score
时间窗: 3.5 years
on 3.5 years after the start of the test
次要结局
- Change of memory performance index score(three months, six months, 1.5 years, 2.5 years and 3.5 years after the start of the test)
- Convertion rate from MCI to dementia(1.5 years and 3.5 years after the start of the test)
- Revertion rate from MCI to normal state(1.5 years and 3.5 years after the start of the test)
- Convertion rate from nomal state to MCI(1.5 years and 3.5 years after the start of the test)
- Questionnaire(1.5 years and 3.5 years after the start of the test)
- Clinical findings at diagnosis of MCI and dementia(1.5 years and 3.5 years after the start of the test)
- Physical function (grip strength)(1.5 years and 3.5 years after the start of the test)
- Aging index (weight, BMI, blood pressure)(1.5 years and 3.5 years after the start of the test)
- Urinary sulforaphane glucosinolate metabolites concentration(1.5 years and 3.5 years after the start of the test)
研究者
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