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临床试验/NCT04038190
NCT04038190已完成2 期

A Cluster-randomized Trial of a Behavioral Activation Intervention Administered in a College Freshman Orientation Course

University of Kansas2 个研究点 分布在 1 个国家目标入组 572 人开始时间: 2019年9月5日最近更新:
适应症
干预措施

试验速览

阶段
2 期
状态
已完成
入组人数
572
试验地点
2
主要终点
alcohol consumption

研究概览

简要总结

The transition from high school to college is a developmentally sensitive period that is high risk for escalations in alcohol use. Although risky drinking is a common problem among freshmen, engagement in treatment services is very low. The proposed study will test a behavioral activation intervention that addresses factors limiting participation in standard treatment services by targeting alcohol use indirectly, by directly addressing concerns most relevant to incoming college freshmen, and by integrating an intervention into the college curriculum.

详细描述

The transition from high school to college is a developmentally sensitive period that is high risk for escalations in alcohol use. Although risky drinking is a common problem among freshmen, engagement in treatment services is very low. Low rates of engagement with treatment resources may occur because interventions target drinking directly at a time when students may be uninterested in changing their drinking. Moreover, with a targeted focus on alcohol use, current interventions also do not address the concerns of incoming freshmen, such as stress and sleep. Approaches that address the problems students are most concerned about, that also indirectly reduce drinking, may be particularly effective.

Behavioral activation (BA) is an intervention that indirectly addresses psychopathy by guiding individuals to identify goals in their lives, and encouraging individuals to engage in reinforcing activities that align with their goals (Lejuez et al, 2001). While initially used to treat depression, BA has been efficaciously applied to substance use because BA acts on the same reinforcement process implicated in problem drinking. BA addresses drinking without specific reference to alcohol use by focusing on engagement in reinforcing activities that align with students' goals. A pilot study provided initial indication that a brief BA intervention administered in a semester-long freshman orientation course resulted in a significant decrease in drinking-related problems, compared to standard orientation (Reynolds et al. 2011). Notably, the approach never raised the issue of drinking unless raised by a student themselves.

The purpose of the study is to conduct a fully powered cluster randomized trial testing BA administered in a semester-long (16 week) freshman orientation course, compared to a standard orientation course in 540 freshmen spread over 36 course sections (18 sections each of the BA and standard orientation format). A 5-month post-treatment assessment will measure durability of effects. Mediation analyses will test mechanisms of action and moderation analyses will examine factors related to efficacy. A random sample of 20% of participants will complete a 17 month follow up, which will occur at the end of their sophomore year of college, to examine long term effects. With this proposed R01, the investigators will test a promising intervention with BA that addresses factors limiting participation in other programs by not targeting alcohol directly and by integrating an intervention into college curriculum, with the additional benefit of testing mediators to guide future work. This application represents a first step toward developing an intervention course that could be widely disseminated to address the persistent college drinking problem and its many consequences.

研究设计

研究类型
Interventional
分配方式
Randomized
干预模型
Parallel
主要目的
Prevention
盲法
Single (Participant)

入排标准

年龄范围
17 Years 至 —(Child, Adult, Older Adult)
性别
All
接受健康志愿者

入选标准

  • College freshmen enrolled in UNIV 101 freshman seminar courses at the University of Kansas assigned to the study

排除标准

  • 未提供

研究组 & 干预措施

Behavioral Activation Course

Experimental

Behavioral activation course condition administered in a college freshman orientation seminar

干预措施: behavioral activation (Behavioral)

Standard Orientation Course

No Intervention

Standard freshman orientation seminar course condition

结局指标

主要结局

alcohol consumption

时间窗: baseline, 2 months, 4 months, and 8 months; 17 months for participants in Years 1-2

Alcohol-Use Disorders Identification Test- Consumption Questions (AUDIT-C), which are the first three items of the AUDIT 10-item measure that asses frequency of drinking, typical quantity, and frequency of heavy drinking occasions (Saunders et al, 1993; Bush et al, 1998; DeMartini et al 2012). Responses are on a likert scale ranging from 0-4. The 3 items are summed for a total score with a possible range of 0-12, with higher scores indicating riskier drinking behavior.

exceeding clinical cutoff of 8+ for hazardous/harmful drinking

时间窗: baseline, 2 months, 4 months, and 8 months; 17 months for participants in Years 1-2

The Alcohol-Use Disorders Identification Test (AUDIT) is designed to assess hazardous alcohol use and alcohol-related problems. The AUDIT has 10 items that assesses frequency of drinking, typical quantity, frequency of heavy drinking, impaired control over drinking, increased salience of drinking, morning drinking, guilt after drinking, blackouts, alcohol-related injuries, and others concerned about (Saunders et al, 1993). Responses are on a likert scale ranging from 0-4. The 10 items are summed for a total score with a possible range of 0-40, with higher scores indicating greater likelihood of hazardous drinking behavior.

high-intensity drinking (2+ times in excess of NIAAA low risk drinking guidelines for males and females)

时间窗: baseline, 2 months, 4 months, and 8 months; 17 months for participants in Years 1-2

The 30-day Time Line Follow Back-Computerized (TLFB-C) assessment will be used to measure alcohol consumption in the past 30 days (Sobell et al, 1996; Sobell \& Sobell, 1992; Sobell \& Sobell, 2008). The measure will be used to obtain the frequency at which individuals engaged in high-intensity drinking of 8+ drinks for males or 10+ drinks for females in one occasion.

alcohol-related problems

时间窗: baseline, 2 months, 4 months, and 8 months; 17 months for participants in Years 1-2

Alcohol-Use Disorders Identification Test- Problem Questions (AUDIT-P) are the last 7 items of the full AUDIT that assess increased salience of drinking, morning drinking, guilt after drinking, blackouts, alcohol-related injuries, and drinking that others are concerned about (Saunders et al, 1993; O'Hare \& Sherrer, 2005). Responses are on a likert scale ranging from 0-4. The 7 items are summed for a total score with a possible range of 0-28, with higher scores indicating greater alcohol-related problems.

次要结局

  • stress(baseline, 2 months, 4 months, and 8 months; 17 months for participants in Years 1-2)
  • binge eating(baseline, 2 months, 4 months, and 8 months; 17 months for participants in Years 1-2)
  • depression(baseline, 2 months, 4 months, and 8 months; 17 months for participants in Years 1-2)

研究者

申办方类型
Other
责任方
Sponsor

研究点 (2)

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