Diffüz Parankimal Akciğer Hastalarında Kırılganlık Düzeyi, Egzersiz Kapasitesi ve Denge Değerlendirilmesi
试验速览
- 阶段
- 不适用
- 状态
- 尚未招募
- 入组人数
- 28
- 试验地点
- 1
- 主要终点
- frailty level
研究概览
简要总结
There are very few studies in the literature examining the frailty levels of diffuse parenchymal lung disease (DPLD) patients and its effect on their functional status despite the high prevalance of frailty in patients with DPLD This observational study aims to learn about the relationship between frailty and functional capacity and balance in DPLD patients compared to healthy subjects.
详细描述
The aim of the study is to evaluate the relationship between the level of frailty and exercise capacity, respiratory functions, diffusion capacity, balance level, postural changes, activities of daily living, peripheral muscle strength and quality of life parameters in DPLD patients. The second aim is to compare diffuse parenchymal lung patients and the healthy control group in terms of these parameters.
研究设计
- 研究类型
- Observational
- 观察模型
- Case Control
- 时间视角
- Prospective
入排标准
- 年龄范围
- 30 Years 至 65 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •Being diagnosed with Diffuse parenchymal lung according to the American Thoracic Society/European Respiratory Society (ATS/ERS) criteria,
- •Being between the ages of 30-65,
- •Being literate,
- •Being willing to participate in the research,
- •Being clinically stable and having any accompanying comorbid conditions (such as hypertension, diabetes) under control,
- •Not having any orthopedic, metabolic or neurological problems that may prevent evaluation of peripheral muscle strength, balance and exercise capacity.
排除标准
- •Having recently experienced syncope,
- •Having a history of unstable cardiovascular disease,
- •Having been hospitalized due to exacerbation in the last 3 months,
- •Having received pulmonary rehabilitation in the last 12 months,
- •Having a neurological disease,
- •Being dependent and using a walking aid while performing the person's daily life activities,
- •Having a pacemaker,
- •Having a diagnosis of lung cancer
结局指标
主要结局
frailty level
时间窗: 1 time which will be in one day
evaluation of frailty level with Fried Frailty Criteria which are weight loss existence, muscle strength, physical activity (will be measured with International Physical Activity Questionnaire), mobility (will be measured by 4-meter walking test), and depression level. Fried frailty phenotype consists of five criteria: loss, exhaustion, physical inactivity, low hand grip strength, and slow walking speed. Patients who have three or more of these criteria are defined as frail, those who have one or two criteria, are defined as prefrail, and none of the criteria are defined as robust.
次要结局
- comorbidity assesment(1 time which will be in one day)
- posture analysis(day 1)
- quality of life evaluation(day 1)
- exercise capacity(1 time which will be in one day)
- pulmonary function measurement(day 1)
- investigation of diffusion capacity of the lung(day 1)
- balance measurement(day 1)
- posture related conditions measurement(day 1)
- posture related (scapular motion)conditions existence measurement(day 1)
- evaluation of participation to daily life activities(day 1)
- peripheral muscle strength(day 1)
研究者
Aynur Demirel
PT, PhD, Assoc. Prof.
Hacettepe University