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临床试验/NCT07502326
NCT07502326已完成不适用

Association Between Changes in Integrated Rehabilitation Functional Assessment and Discharge Destination in Patients With Stroke in a Post-Acute Rehabilitation Hospital: A Retrospective EMR-Based Observational Study

SeongKi Min1 个研究点 分布在 1 个国家目标入组 119 人开始时间: 2024年1月1日最近更新:
适应症
干预措施

试验速览

阶段
不适用
状态
已完成
发起方
入组人数
119
试验地点
1
主要终点
Discharge Destination

研究概览

简要总结

This retrospective observational study will evaluate whether changes in functional status during inpatient rehabilitation are associated with discharge destination in patients with stroke treated at a post-acute rehabilitation hospital. The study will use de-identified electronic medical record data from adult patients with stroke who were admitted to Zenith Hospital and discharged between January 1, 2024 and March 31, 2025.

Integrated rehabilitation functional assessment data obtained at admission and discharge will be analyzed, including the Korean Modified Barthel Index (K-MBI), Functional Ambulation Category (FAC), Berg Balance Scale (BBS), Mini-Mental State Examination (MMSE), and Manual Function Test (MFT). The main objective is to determine whether changes in these measures during hospitalization are associated with discharge destination, defined as home discharge versus transfer to another institution.

A total of 119 eligible patients were included in the final analysis. Only existing de-identified EMR data will be used. No direct participant contact, additional data collection, or protocol-assigned intervention will occur. Findings from this study may provide evidence to support discharge planning and community reintegration strategies for patients with stroke receiving post-acute rehabilitation.

详细描述

Stroke is a major cause of disability, and discharge destination after inpatient rehabilitation is an important clinical and social outcome. In post-acute rehabilitation settings, integrated functional assessments are routinely performed during hospitalization, but there is limited evidence on whether the magnitude of functional improvement between admission and discharge is associated with home discharge among patients with stroke in Korean rehabilitation hospitals. This study is designed to address that gap using de-identified electronic medical record data from a post-acute rehabilitation hospital.

The primary purpose of this study is to investigate the association between changes in integrated rehabilitation functional assessment scores during hospitalization and discharge destination in patients with stroke. Specifically, the study will evaluate whether changes in Korean Modified Barthel Index (K-MBI), Functional Ambulation Category (FAC), Berg Balance Scale (BBS), Mini-Mental State Examination (MMSE), and Manual Function Test (MFT) are associated with home discharge versus transfer to another institution.

This is a retrospective observational study conducted at Zenith Hospital, a post-acute rehabilitation hospital in the Republic of Korea. The study population will include adult patients with stroke who were admitted to the rehabilitation ward and discharged between January 1, 2024 and March 31, 2025. Eligible participants must have integrated rehabilitation functional assessment data recorded in the electronic medical record at both admission and discharge. Patients with missing admission or discharge functional assessment data, terminal illness preventing rehabilitation, in-hospital death, or insufficient EMR data for analysis will be excluded.

The main independent variables are changes in functional assessment scores between admission and discharge, including delta K-MBI, delta FAC, delta BBS, delta MMSE, and delta MFT. The primary outcome is discharge destination, categorized as home discharge or transfer to another institution. Covariates available in the EMR, such as age, sex, length of stay, and stroke type, will also be analyzed as potential confounders.

The study procedures are as follows: the hospital medical records team will identify potentially eligible patients according to the inclusion and exclusion criteria; all direct identifiers will be removed from the EMR data; a study-specific de-identified code will be assigned; and only de-identified data will be provided to the investigator for analysis. The investigator will calculate functional changes and perform statistical analyses to identify factors associated with discharge destination. There will be no participant contact, no prospective enrollment, no survey administration, and no intervention assigned as part of this study.

研究设计

研究类型
Observational
观察模型
Cohort
时间视角
Retrospective

入排标准

年龄范围
19 Years 至 —(Adult, Older Adult)
性别
All
接受健康志愿者

入选标准

  • Patients with stroke who were admitted to and discharged from the convalescent rehabilitation ward at Zenith Hospital between January 1, 2024, and March 31, 2025
  • Age 19 years or older
  • Integrated rehabilitation functional assessment data available in the electronic medical record at both admission and discharge, including Korean Modified Barthel Index (K-MBI), Functional Ambulation Category (FAC), Berg Balance Scale (BBS), Mini-Mental State Examination (MMSE), and Manual Function Test (MFT)

排除标准

  • Missing admission or discharge functional assessment data
  • Patients with terminal illnesses that made rehabilitation treatment infeasible, such as advanced cancer or end-stage heart failure
  • In-hospital death or transfer before discharge assessment, resulting in no discharge functional assessment data
  • Insufficient electronic medical record data for the study analysis

研究组 & 干预措施

Stroke Rehabilitation Cohort

Adult patients with stroke who received inpatient rehabilitation at Zenith Hospital and met the study eligibility criteria.

干预措施: Inpatient Rehabilitation (Other)

结局指标

主要结局

Discharge Destination

时间窗: At discharge from inpatient rehabilitation, up to 15 months after admission

Discharge destination assessed at discharge from inpatient rehabilitation, categorized as home discharge or transfer to another institution.

Discharge Destination

时间窗: At discharge from inpatient rehabilitation

Discharge destination assessed at discharge from inpatient rehabilitation, categorized as home discharge or transfer to another institution.

次要结局

  • Change in Korean Modified Barthel Index (K-MBI) score(From admission to discharge from inpatient rehabilitation, up to 15 months)
  • Change in Functional Ambulation Category (FAC) score(From admission to discharge from inpatient rehabilitation, up to 15 months)
  • Change in Berg Balance Scale (BBS) score(From admission to discharge from inpatient rehabilitation, up to 15 months)
  • Change in Mini-Mental State Examination (MMSE) score(From admission to discharge from inpatient rehabilitation, up to 15 months)
  • Change in Manual Function Test (MFT) score(From admission to discharge from inpatient rehabilitation, up to 15 months)
  • Change in Korean Modified Barthel Index (K-MBI) score(Within 3 days after admission and within 3 days before discharge from inpatient rehabilitation)
  • Change in Functional Ambulation Category (FAC) score(Within 3 days after admission and within 3 days before discharge from inpatient rehabilitation)
  • Change in Berg Balance Scale (BBS) score(Within 3 days after admission and within 3 days before discharge from inpatient rehabilitation)
  • Change in Mini-Mental State Examination (MMSE) score(Within 3 days after admission and within 3 days before discharge from inpatient rehabilitation)
  • Change in Manual Function Test (MFT) score(Within 3 days after admission and within 3 days before discharge from inpatient rehabilitation)

研究者

发起方
SeongKi Min
申办方类型
Other
责任方
Sponsor Investigator
主要研究者

SeongKi Min

Hospital Director

Zenith Hospital

研究点 (1)

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