NCT00004582已完成2 期
A Phase II Study of ABT-378/Ritonavir and Efavirenz in Multiple Protease Inhibitor-Experienced Subjects
适应症
相关药物
试验速览
- 阶段
- 2 期
- 状态
- 已完成
- 发起方
- ViRx
- 试验地点
- 2
研究概览
简要总结
The purpose of this study is to see if ABT-378/ritonavir plus efavirenz is safe and effective in lowering the amount of HIV in the blood of patients who have been treated with more than 1 protease inhibitor (PI).
详细描述
All patients take ABT-378/ritonavir and efavirenz; there are no placebos in this study. Patients take study medications for 48 weeks, during which time there will be 15 study visits. There is a possibility of a study extension after 48 weeks.
研究设计
- 研究类型
- Interventional
- 主要目的
- Treatment
- 盲法
- None
入排标准
- 年龄范围
- 0 Years 至 —（Child, Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Patients may be eligible for this study if they:
- •Are HIV-positive.
- •Have a viral load (level of HIV in the blood) of at least 1,000 copies/ml.
- •Have been receiving stable (no changes) anti-HIV treatment that includes at least 1 PI for at least 8 weeks prior to study entry.
- •Have received more than 1 PI for at least 12 weeks each at some time in the past.
排除标准
- •Patients will not be eligible for this study if they:
- •Have had any active opportunistic (AIDS-related) infections within the past 30 days.
- •Have ever received nonnucleoside reverse transcriptase inhibitors (NNRTIs), such as delavirdine, nevirapine, or efavirenz.
- •Have received certain medications.
- •Are pregnant or breast-feeding.
- •Abuse alcohol or drugs.
研究者
研究点 (2)
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