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临床试验/NCT06146400
NCT06146400尚未招募不适用

Role of CBC Parameters in Early Diagnosis of Bacterial and Viral Pediatric Pneumonia

Assiut University0 个研究点目标入组 100 人开始时间: 2023年12月最近更新:
适应症

试验速览

阶段
不适用
状态
尚未招募
入组人数
100
主要终点
role of CBC parameters and ratios in early diagnosis of pediatric pneumonia - Detecting the role of Complete Blood Picture parameters and ratios in early diagnosis of pediatric pneumonia CBC Parameters in diagnosis pediatric pneumonia

研究概览

简要总结

Detection of the role of Complete Blood Count (CBC) parameters in early diagnosis of pediatric pneumonia

-Testing the ability of Complete Blood Count (CBC) parameters (N/L ratio, PLT /MPV ratio, MPV and other parameters) to differentiate between viral and bacterial pneumonia.

详细描述

Pneumonia is the leading cause of hospitalizations and death among children with nearly 120 million new cases and one million deaths every year.

  • Viruses are the main cause of pneumonia in infants and toddlers between 30 days and 2 years old.
  • Children 2 to 5 years old, respiratory viruses are also common with the rise of cases related to S. pneumoniae and H. influenzae type B and other bacterial organisms.

Viral pneumonia caused by , respiratory syncytial virus, which are the most common cause of community- acquired pneumonia in children younger than 5 years. Streptococcus pneumoniae is the most common bacterial cause across all age groups. Other important bacterial causes in children younger than 5 years include Hemophilus influenzae, Streptococcus pyogenes, Staphylococcus aureus, and Moraxella catarrhalis.

Parapneumonic effusion/empyema (PPE/EP), necrosis of lung parenchyma (NC), and lung abscess (AB), are serious complication of pediatric pneumonia. Because of these serious complications, early diagnosis of the causative organism is very important to start the proper treatment and avoid these serious complications.

Complete Blood Picture (CBC) is one of the most important preliminary routine investigations for diagnosis and monitoring of infection.

研究设计

研究类型
Observational
观察模型
Case Control
时间视角
Prospective

入排标准

年龄范围
1 Year 至 5 Years(Child)
性别
All
接受健康志愿者

入选标准

  • Newly suspected cases of pneumonia from age o 1 month to 5 years in 2 age groups

排除标准

  • Age group >5 years
  • Already diagnosed patient who is under treatment

结局指标

主要结局

role of CBC parameters and ratios in early diagnosis of pediatric pneumonia - Detecting the role of Complete Blood Picture parameters and ratios in early diagnosis of pediatric pneumonia CBC Parameters in diagnosis pediatric pneumonia

时间窗: Baseline

CBC parameters and ratios N/L Ratio PLT/MPV ratio ,MPV in differentiation between bacterial and viral pneumonia

次要结局

未报告次要终点

研究者

申办方类型
Other
责任方
Principal Investigator
主要研究者

Amira Abdeltwab saber

Principle investigator

Assiut University

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