Effects of oral protein load on the rate of gastric emptying, intragastric meal distribution, gastrointestinal hormone release, appetite sensations and energy intake in lean subjects.

Dr Natalie Luscombe-Marsh0 个研究点目标入组 32 人开始时间: 2011年7月8日最近更新: 2020年1月13日

适应症

试验速览

暂无简介。

•non-obese with a body mass index of 19-25kg/m2 and weight stable (<5% fluctuation in body weight in previous 3 months)

•1) Significant gastrointestinal symptoms; disease or surgery 2) Use of prescribed or non-prescribed medications (including vitamins and herbal supplements) which may effect energy metabolism, GI function, body weight or appetite (eg domperidone and cisapride, anticholinergic drugs (eg. atropine), metoclopramide, erythromycin, hyoscine, orlistate, green tea extracts, astragalus, St. johns Wort etc.) 3) Diabetes mellitus, epilepsy, cardiovascular or respiratory disease, or any other significant illness as assessed by the investigator 4) Intake of >20g alcohol on a daily basis 5) Smokers (cigarettes, cigars, marijuana) 6) In female subjects, pregnancy or lactation. A pregancy test will be performed in all female subjects of childbearing potential, using a urine sample, prior to commencement of the study and subsequently prior to each study day 7) Restrained eaters, as determined by a score of >12 on the eating restraint questionnaire component of the 3 factor eating questionnaire 8) Donation of blood in the past 12 weeks prior to enrolment in the study. Subjects will also be advised to abstain from donating blood for 12 weeks following study completion 9) Consumption of a vegetarian diet.

发起方

Dr Natalie Luscombe-Marsh