Australian Multicentre Colonic Endoscopic Mucosal Resection (ACE/EMR) Study
试验速览
- 阶段
- 不适用
- 状态
- 进行中（未招募）
- 发起方
- 入组人数
- 3,072
- 试验地点
- 1
- 主要终点
- Technical success for Endoscopic resection
研究概览
简要总结
A prospective, multicentre, observational study of all patients referred for endoscopic resection of sessile colorectal polyps sized ≥20 mm conducted with intention to treat analysis.
详细描述
A prospective, multicentre, observational study of all patients referred for endoscopic resection of sessile colorectal polyps sized ≥20 mm conducted with intention to treat analysis. Detailed data regarding lesion characteristics (size, location, Paris classification, granular or non-granular surface morphology and Kudo pit pattern), procedural, clinical and histological outcomes and complications are noted. Multivariate analysis will be performed to identify risk factors for Endoscopic Mucosal Resection failure and adenoma recurrence at follow-up colonoscopy.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Prospective
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Large sessile polyp (equal to or greater than 20mm)
- •Intention to perform EMR
- •Aged 18 years or older
排除标准
- •Colonic polyps less than 20mm
- •Aged younger then 18 years.
结局指标
主要结局
Technical success for Endoscopic resection
时间窗: 6-60 months
To determine the safety, efficacy and predictors of success for Endoscopic Mucosal Resection of large sessile colorectal polyps. The utility of endoscopic criteria to stratify for the risk of Submucosal Invasive Cancer was also assessed.
次要结局
未报告次要终点
研究者
Professor Michael Bourke
Dr Michael Bourke
Western Sydney Local Health District