A Cognitive Occupation-Based programme for people with Multiple Sclerosis (COB-MS): a randomised pilot trial to improve cognition and daily functioning for people with multiple sclerosis

I Galway0 个研究点目标入组 94 人开始时间: 2019年9月4日最近更新: 2024年4月8日

适应症

试验速览

2020 Protocol article in https://www.ncbi.nlm.nih.gov/pubmed/32183874 protocol (added 19/03/2020) 2023 Other publications in https://pubmed.ncbi.nlm.nih.gov/37493191/ (added 27/07/2023) 2024 Preprint results in https://doi.org/10.21203/rs.3.rs-4151380/v1 (added 28/03/2024)

•People with MS:
•1. Aged 18 years of age or older
•2. Fluent in written and spoken English
•3. Diagnosis of multiple sclerosis
•4. Cognitive difficulties, as shown by a score of >22 on the MSNQ
•5. Clinically stable (we define clinically stable” as not having an active relapse)
•6. Can provide informed consent
•7. No neurologic history other than MS, including evidence of current dementia
•8. No history of major depressive disorder, schizophrenia, or bipolar disorder I or II
•9. No history of diagnosed substance use or dependence disorder
•10. Not currently undergoing any other form of cognitive rehabilitation
•11. Living in the community
•Occupational Therapists:
•1. Currently working in Ireland as an occupational therapist
•2. CORU-registered
•3. Have experience working with people with MS
•4. Can commit to the requirements of the study

•People with MS:
•1. Cognitive impairment that would affect reliable participation or capacity to give informed consent
•2. Are incarcerated or institutionalized
•3. Significant neurological condition or organic brain damage (unrelated to MS).
•Occupational Therapists:
•1. Not meeting the inclusion criteria

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