Concomitant Infection of Intestinal Parasites and Helicobacter Pylori in Sohag University Hospital
试验速览
- 阶段
- 不适用
- 入组人数
- 200
- 试验地点
- 1
- 主要终点
- Compare the prevalence of intestinal parasitic infections among positive and negative H.pylori infected outpatients in Sohag University Hospital
研究概览
简要总结
Intestinal parasitic infections such as Giardia lamblia, Entamoeba histolyica and Enterobius Vermicularis are among the most common infections worldwide.So parasitic infections are considered one of the major health problems in the world especially in developing countries.
Helicobacter pylori is a gram-negative,helical-shaped,motile bacillus bacterium,which colonizes the gastric mucosa.
H.pylori bacterium secretes urease,a special enzyme that converts urea to ammonia.
Ammonia reduces the stomach's acidity .This risk factor allows pathogenic intestinal protozoa such as G.lamblia to take the opportunity to cross through the stomach's increased pH and cause disease.
研究设计
- 研究类型
- Observational
- 观察模型
- Case Control
- 时间视角
- Prospective
入排标准
- 年龄范围
- 1 Year 至 —（Child, Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •patients complaining of dyspepsia , abdominal burning pain,diarrhea,dysentery,of persons of any age or sex group.
排除标准
- •patients taking antibiotics within the previous four weeks, proton pump inhibitors within the previous two weeks, or anti-parasitic drugs within the previous two weeks.
结局指标
主要结局
Compare the prevalence of intestinal parasitic infections among positive and negative H.pylori infected outpatients in Sohag University Hospital
时间窗: 18 weeks following the start point of the study
Collection of 200 stool samples (100 positive and 100 negative for H.pylori) then parasitological examination done for all samples
次要结局
- Evaluate the prevalence of intestinal parasitic infection among H.pylori infected outpatients in Sohag University Hospital(18 weeks following the start point of the study)
研究者
Asmaa Nabil Abouzeid
Demonstrator at medical parasitology department at faculty of medicine Sohag university
Sohag University