An open clinical trial of Siddha drug Karunchoorai chooranam (Internal medicine) and Kodiveli Thylam (External Medicine) in the treatment of kalanjagapadai (Psoriasis)

It is a single non-randomised , open label trial to determine the therapeutic efficacy  of KARUNCHOORAI CHOORANAM (prepared from herbal constituents) in patients with  PSORIASIS (KALANJAGAPADAI). Karunchoorai chooranam consists of  Capparis sepiaria, Plumbago indica, Enicostemma axillare, Toddalia asiatica, Piper nigrum, Gymnema sylvestre, Corallocarpus epigaeus, Acaci anilotica and Stercularia foedita*.*  All the ingredients are purified, powdered and stored in an air tight container.In this  trial 40 patients will be recruited and the trial drug will be administered 2 gram twice a day for a period of 48 days. During the trial period if any AE/SAE/SUSAR will be noticed and referred to pharmaco vigilance department in NIS and further management will also be given in NIS OPD/IPD. The entire trial will be monitored by the research monitoring committee of NIS. During this trial all the safety efficacy parameters will be recorded in the CRF. After completion of the trial all the study related data will be analysed statistically. The outcome of this trial will be published in Indian Journal of Medical Research.