Evaluation of the Axonemal Dynein Heavy Chain 5 and Creatine Kinase Concentration in Cervical Fluid for Early Detection of the Ectopic Pregnancy
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 85
- 试验地点
- 1
- 主要终点
- Concentration of Axonemal Dynein Heavy Chain 5
研究概览
简要总结
Patients who have doubt for ectopic pregnancy will be enrolled for our study. These patients will be determined with using irregular increased human chorionic gonadotropin (beta-HCG) results and no embryo reported ultrasonography results. Plasma and cervical fluid samples will be taken from these patients and axonemal dynein heavy chain 5 and creatine kinase levels of samples will be compared between patients who have doubt for ectopic pregnancy and patients who have intrauterine pregnancy. Concentration of these proteins in samples will be evaluated. If any difference will be found between groups in favour of ectopic pregnancy, these results might be interpreted as these proteins useful for early detecting of the ectopic pregnancy.
研究设计
- 研究类型
- Observational
- 观察模型
- Case Control
- 时间视角
- Cross Sectional
入排标准
- 年龄范围
- 18 Years 至 45 Years（Adult）
- 性别
- Female
- 接受健康志愿者
- 否
入选标准
- •Doubted ectopic pregnancy
- •Without any finding about intrauterine pregnancy in ultrasonography results
- •Without any vaginal bleeding
- •Having irregular pregnancy test results
- •Beta-HCG results should be at least upper than 100 milli-International unit (mIU/ml)
- •Having fist trimester pregnancy for intrauterine pregnancy group
- •Without any emergency findings
排除标准
- •Doubted incomplete abortion
- •Having vaginal bleeding
- •Having ultrasound results which include intrauterine embryo report
- •Having lower than 100 mIU/ml beta-HCG results
- •Without fetal heart rate in intrauterine pregnancy group
- •Having older than fist trimester pregnancy for intrauterine pregnancy group
- •Having emergency findings
结局指标
主要结局
Concentration of Axonemal Dynein Heavy Chain 5
时间窗: 1 year
Concentration of creatine kinase
时间窗: 1 year
次要结局
未报告次要终点