Efficacy of Short-message-based Re-education (SMRE) on Helicobacter Pylori Eradication
试验速览
- 阶段
- 4 期
- 发起方
- 入组人数
- 310
- 试验地点
- 1
- 主要终点
- The difference of H. pylori eradication rate between two groups
研究概览
简要总结
Helicobacter pylori (H. pylori) is a pathogen that infects more than 50% of the human population, resulting in high healthcare costs worldwide. However, H. pylori eradication rate is low nowadays and patients's compliance is one of the most important effective factors.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- None
入排标准
- 年龄范围
- 18 Years 至 70 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •outpatients aged 18-70 years
- •confirmed diagnosis of H. pylori infection by at least one of the following methods: 13C-urea breath test, histology, rapid urease test or bacterial culture
- •an intention of H. pylori eradication treatment and have written inform consent
- •ability to read short messages on the mobile phone
排除标准
- •advanced chronic disease that would not allow the patient to complete the treatment or follow-up or attend visits
- •allergy to any of the drugs used in this study
- •previous Helicobacter Pylori eradication treatment
- •pregnancy or breastfeeding (female participants with childbearing potential were required to use medically accepted contraception for the duration of the study)
- •taking antibiotics or PPIs or bismuth salts within four weeks
- •previous gastrointestinal surgery
研究组 & 干预措施
Short-message-based Re-education group
Patients receive oral and written education before H. pylori eradication therapy at first, then they receive short message re-education twice per day during therapy.
Both the content of the oral and written education and the short message re-education are same.
干预措施: Short-message-based Re-education (Behavioral)
conventional education group
Patients only receive oral and written education before H. pylori eradication therapy.
干预措施: conventional education (Behavioral)
结局指标
主要结局
The difference of H. pylori eradication rate between two groups
时间窗: 8 months
次要结局
- Rate of non-compliance with instructions between 2 groups(8 months)
研究者
Yanqing Li
Vice president of Qilu Hospital
Shandong University