ACTRN12619000730101尚未招募1 期
Antiarrhythmic properties and safety of phenytoin or dantrolene in patients with cardiomyopathy; a randomised, double blinded, placebo controlled trial
niversity of Newcastle0 个研究点目标入组 105 人开始时间: 2019年5月14日最近更新:
适应症
试验速览
- 阶段
- 1 期
- 状态
- 尚未招募
- 发起方
- 入组人数
- 105
研究概览
简要总结
暂无简介。
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomised controlled trial
- 主要目的
- Treatment
- 盲法
- Blinded (masking used)
入排标准
- 年龄范围
- 18 Years 至 85 Years（—）
- 性别
- All
入选标准
- •with cardiomyopathy, Ejection Fraction<35%
- •with Implantable Cardioverter Defibrillator (ICD) or Cardiac Resynchronisation Therapy (CRT)
- •Aged 18 to 85
排除标准
- •Pregnant or breastfeeding females
- •Childbearing age women (not on 2 contraceptive methods including non-oestrogen based OCP)
- •Childbearing age women on oestrogen based OCP
- •Inability to provide informed consent
- •Patients with end stage kidney disease (eGFR<30) and patients on Dialysis
- •Liver cirrhosis
- •Patients with Aspartate transaminase (AST), and alanine transaminase (ALT) > 3 times upper limit of institutional normal value (ULN) on 2 measurements separated by at least 5 days
- •Being prescribed the drug verapamil
研究者
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