Effects of a Short-term Aerobic Interval Exercise Program on Cardiac Fat and Function in Women With Obesity: A Pilot Study
试验速览
- 阶段
- 不适用
- 状态
- 撤回
- 试验地点
- 1
- 主要终点
- Changes in Cardiac Function
研究概览
简要总结
The overall goal of this project is to the study the effects of an aerobic interval training program on cardiac fat, and its relationship to cardiac function using cardiac Magnetic Resonance Imaging.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- None
入排标准
- 年龄范围
- 18 Years 至 40 Years（Adult）
- 性别
- Female
- 接受健康志愿者
- 是
入选标准
- •females, age 18-40 years old, body mass index (BMI) ≥ 30 kg/m2 and < 39.9 kg/m2, without known metabolic and/or cardiovascular disease
排除标准
- •known CV, metabolic or pulmonary diseases or conditions, muscular-skeletal injuries (i.e. spine, knees, hips or shoulders, taking medications that affect endocrine or cardiovascular function, hypertension, being engaged in moderate intensity exercise more than two times per week or moderate-high intensity training of any type and frequency, being pregnant, cigarette smoking, having non-removable pieces or devices incompatible with DXA and CMR assessment
研究组 & 干预措施
Aerobic interval
Aerobic interval will consist of a supervised aerobic interval training sessions 3 times/week. Duration will range between 45-50 min/session depending on the exercise energy expenditure (target expenditure ~450-500kcal/session). Each interval will have a total duration of 5 min, and it will be divided into 2 periods. The first period will consist of 3 minutes of high-intensity activity at 70-85% of predicted HRmax, and for the second period the intensity will be reduced to 60-65% of predicted HRmax for 2 minutes. The training sessions will be carried out outdoors at the trails located on campus. The activity will consist of walking and/or light jogging. The speed/incline will be changed depending on the participants' heart rate and perception using the Borg's rating of perceived exertion (RPE) as needed. The RPE for the first period range will be 13-17 (15-17 at the end of the period) and 10-12 for the second period.
干预措施: Aerobic Interval Training (Other)
Control group
Participants in the control group will not participate in the training programs.
结局指标
主要结局
Changes in Cardiac Function
时间窗: 2 assessment points: at baseline and week 5
Cardiac Function will be measured using cardiac Magnetic Resonance
Changes in Cardiac Adipose Tissue (CAT)
时间窗: 2 assessment points: at baseline and week 5
CAT will be measured using cardiac Magnetic Resonance
次要结局
- Changes in Body Composition(2 assessment points: at baseline and week 5)
- Changes in Blood Pressure(2 assessment points: at baseline and week 5)
- Changes in Cardiorespiratory Function(2 assessment points: at baseline and week 5)
- Changes in Muscular Strength(2 assessment points: at baseline and week 5)
研究者
Maria Fernandez Del Valle
Principal Investigator
Southern Illinois University Edwardsville