Assessment of neutrophil to lymphocyte ratio dynamics before and after periodontal therapy in stage iii periodontitis-a clinico-hematological study.
试验速览
- 阶段
- 不适用
- 状态
- 尚未招募
- 发起方
- 入组人数
- 18
- 试验地点
- 1
- 主要终点
- periodontits is associated with neutrophil to lymphocyte ratio and that periodontal therapy is able to bring down the levels .
研究概览
简要总结
This study is a clinico hematological study where 18 patients of both gender with stage 3 periodontitis, satisfying all the inclusion criteria will be enrolled for the study. This study evaluates neutrophil to lymphocyte ratio in stage 3 periodontitis patients before treatment, after scaling and root planing, and after flap surgery. Initial assessments will include a detailed case history and clinical parameters, with blood samples taken for NLR detection. Patients will receive scaling and root planing and return after 1 month for reevaluation. Those with persistent pockets will undergo flap surgery, with follow up assessments 3 months later. NLR will be compared at these 3 intervals.
研究设计
- 研究类型
- Interventional
- 分配方式
- Na
- 盲法
- Participant Blinded
入排标准
- 年龄范围
- 18.00 Year(s) 至 55.00 Year(s)（—）
- 性别
- All
入选标准
- •Patients of age between 18 and 55 years 2) Patients with stage III Periodontitis.
- •Patients with radiographic evidence of bone loss.
排除标准
- •Current or previous smokers and alcoholics.
- •History of periodontal therapy or antimicrobial therapy within 6 months, or history of orthodontic therapy.
- •Patients with any other systemic diseases.
- •Pregnant, menopause or lactating females.
结局指标
主要结局
periodontits is associated with neutrophil to lymphocyte ratio and that periodontal therapy is able to bring down the levels .
时间窗: all clinical parameters and NLR levels will be measured at baseline,1 month after scaling and root planing and 3 month after flap surgery
次要结局
- to estimate the NLR ratio in Stage III periodontitis before and after periodontal therapy and to evaluate their possible role as an inflammatory marker for periodontal disease.(baseline,1 month after scaling and root planing and 3 month after flap surgery)
研究者
Dr Richa Sherry
Coorg Institute of Dental Sciences