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临床试验/NCT07575776
NCT07575776尚未招募不适用

Effect of Different Flows Using High-Flow Nasal Oxygen (HFNO) on Laryngoscopic View Quality During Videolaryngoscopy

Masarykova Nemocnice v Usti nad Labem, Krajska Zdravotni a.s.0 个研究点目标入组 150 人开始时间: 2026年9月1日最近更新:

试验速览

阶段
不适用
状态
尚未招募
发起方
入组人数
150

研究概览

简要总结

This prospective, multicenter observational study aims to evaluate the effect of different flow rates of high-flow nasal oxygen (HFNO) on the quality of the laryngoscopic view during videolaryngoscopy in adult patients undergoing general anesthesia. Each patient will serve as their own control, with repeated measurements obtained at three different HFNO flow settings (0, 40, and 60 L/min). The study will assess objective and subjective parameters of glottic visualization using standardized scoring systems.

详细描述

Anaesthetic management Anaesthesia induction and airway management will be standardized as far as clinically feasible. Standard monitoring will be applied according to institutional practice. Preoxygenation will be performed using high-flow nasal oxygen (HFNO). General anaesthesia will be induced using standard intravenous agents, followed by administration of neuromuscular blockade to facilitate laryngoscopy. Mask ventilation will be performed as clinically indicated.

Videolaryngoscopy will be performed using a standardized device and blade type whenever possible. All procedures will be performed by anesthesiologists experienced in videolaryngoscopy.

Study procedure

After induction of anaesthesia and achievement of adequate conditions for laryngoscopy, videolaryngoscopy will be performed. During a single laryngoscopic sequence, images of the laryngeal view will be obtained under three predefined HFNO flow conditions:

  • 0 L/min
  • 40 L/min
  • 60 L/min At each flow level, once a stable laryngeal view will be achieved, a still image will be captured using the videolaryngoscope recording system. The laryngoscope position will be maintained as stable as possible during acquisition of all three images. No attempt at tracheal intubation will be made during image acquisition.

研究设计

研究类型
Observational
观察模型
Case Control
时间视角
Prospective

入排标准

年龄范围
18 Years 至 —(Adult, Older Adult)
性别
All
接受健康志愿者

入选标准

  • Age ≥18 years
  • Scheduled for endotracheal intubation under general anesthesia
  • Use of videolaryngoscopy

排除标准

  • Anticipated difficult airway
  • Emergency intubation
  • Contraindications to HFNO
  • Inability to obtain adequate video recording

研究者

发起方
Masarykova Nemocnice v Usti nad Labem, Krajska Zdravotni a.s.
申办方类型
Other
责任方
Principal Investigator
主要研究者

Michal Kalina

Deputy for science and research

Masarykova Nemocnice v Usti nad Labem, Krajska Zdravotni a.s.

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