Effect of Omentectomy on Metabolic Syndrome, Acute Phase Reactants & Inflammatory Mediators in Patients Undergoing LRYGBP: A Randomized Trial
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 24
- 主要终点
- Components of Metabolic Syndrome (Body Mass Index)
研究概览
简要总结
The aim of the present study was to evaluate the additional effect of sudden visceral fat reduction by omentectomy on Metabolic Syndrome, acute phase reactants and inflammatory mediators in patients with morbid obesity undergoing Laparoscopic Roux-en-Y Gastric Bypass.
详细描述
Although weight loss controls Metabolic Syndrome and reduces the level of inflammatory markers in patients with Morbid Obesity, patients may enjoy the benefit achieving metabolic control before significant weight loss occurs.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- None
入排标准
- 年龄范围
- 20 Years 至 65 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •BMI > 35 Kg/m2
- •Metabolic syndrome diagnosed
排除标准
- •Type 1 diabetes
- •Uncontrolled type 2 diabetes
- •Cirrhosis or active hepatitis
- •Pregnancy
- •Recent MI or stroke
结局指标
主要结局
Components of Metabolic Syndrome (Body Mass Index)
时间窗: 1 year
Absolute values are presented, a basal value is provided in a previous outcome measure to determine the improvement.
Components of Metabolic Syndrome (Systolic Blood Pressure)
时间窗: 1 year
Absolute values are presented, a basal value is provided in a previous outcome measure to determine the improvement.
Components of Metabolic Syndrome (Triglycerides)
时间窗: 1 year
Absolute values are presented, a basal value is provided in a previous outcome measure to determine the improvement.
Components of Metabolic Syndrome (Low-Density Lipoproteins)
时间窗: 1 year
Absolute values are presented, a basal value is provided in a previous outcome measure to determine the improvement.
Components of Metabolic Syndrome (Diastolic Blood Pressure)
时间窗: 1 year
Absolute values are presented, a basal value is provided in a previous outcome measure to determine the improvement.
Components of Metabolic Syndrome (Total Cholesterol)
时间窗: 1 year
Absolute values are presented, a basal value is provided in a previous outcome measure to determine the improvement.
Components of Metabolic Syndrome (Glucose)
时间窗: 1 year
Absolute values are presented, a basal value is provided in a previous outcome measure to determine the improvement.
Components of Metabolic Syndrome (Insulin)
时间窗: 1 year
Absolute values are presented, a basal value is provided in a previous outcome measure to determine the improvement.
Components of Metabolic Syndrome (High-Density Lipoproteins)
时间窗: 1 year
Absolute values are presented, a basal value is provided in a previous outcome measure to determine the improvement.
次要结局
- Acute Phase Reactants and Inflammatory Mediators (Interleukine-6)(1 year)
- Acute Phase Reactants and Inflammatory Mediators (C-reactive Protein)(1 year)
- Acute Phase Reactants and Inflammatory Mediators (Tumor Necrosis Factor-alpha)(1 year)
- Acute Phase Reactants and Inflammatory Mediators (Leptin)(1 year)
- Acute Phase Reactants and Inflammatory Mediators (Adiponectin)(1 year)