Neural Mechanisms of the Contextual Interference Effect: A fNIRs and EEG Study
试验速览
- 阶段
- 1 期
- 状态
- 已完成
- 入组人数
- 20
- 试验地点
- 1
- 主要终点
- metabolic measures of neural activity in the dorsolateral prefrontal cortex
研究概览
简要总结
The overall goal of this study is to gain insight into the neural mechanisms of learning multiple tasks. By examination of cognitive and behavioral output during the performance and learning of several computer maze tasks, and through a detailed examination of the neural activity obtained from functional near-infrared (fNIR) and electroencephalography (EEG), it may be possible to gain insight into the impact of the amount of practice and the organization of practice has on learning fine motor skills. This insight may provide direction as to how to better develop instructional and rehabilitation protocols in addition to clinical interventions to facilitate recovery of function, relearning and transfer of cognitive and fine motor skills based upon neural responses to physical practice.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Basic Science
- 盲法
- Single (Participant)
入排标准
- 年龄范围
- 18 Years 至 55 Years（Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •18 to 55 years of age
- •vision correctable to 20/20
- •right-handed
- •English is first language or learned English before age of 5 years
排除标准
- •17 years or younger and 56 years or older
- •have latex or tape adhesives allergies
- •self-exclude if:
- •had a history of seizures, head injury or neurological dysfunction
- •history or diagnosis of depression, schizophrenia or social phobia
- •previous admission to alcohol/drug treatment program or diagnosis of alcohol/drug abuse
- •take medications know to affect neurological function.
研究组 & 干预措施
Practice Schedules
Subjects are randomly assigned to either a blocked or random practice schedule when learning three 3-D computer mazes. A blocked practice schedule is created when the tasks to be learned are presented in a predictable order, while a random practice schedule has tasks presented in a nonsequential, unpredictable order. Neural activity and behavioral measures will differ for the two practice schedules. For memory and transfer, it is predicted that random practice will be better than blocked practice.
干预措施: Practice Order (Behavioral)
结局指标
主要结局
metabolic measures of neural activity in the dorsolateral prefrontal cortex
时间窗: outcomes measured 72 - 96 hours post-training
Functional near infrared spectroscopy (fNIR) uses specific wavelets of light, that are introduced at the scalp to measure changes in the relative ratios of deoxygenated hemoglobin and oxygenated hemoglobin in the capillary beds during brain activity.
次要结局
- Behavioral measures(measured 72-96 hours post training)