Diffusion MRI as a Prognostic Tool in Growth Plate Injuries: A Pilot Study to Assess Feasibility
试验速览
- 阶段
- 不适用
- 入组人数
- 10
- 试验地点
- 1
- 主要终点
- Tissue characterization of growth plate using diffusion MRI
研究概览
简要总结
Children who suffer fractures to the growth plates (physes) of their bones are at risk for premature growth arrest which can lead to long term complications. There is currently no technique to predict who is at risk of growth arrest following a physeal injury. The investigators aim to determine if diffusion MRI (an imaging method to analyze tissue properties) can effectively pick up differences between a healthy growth plate and an injured one. This would allow orthopaedics surgeons to predict which injuries are at a higher risk of growth arrest, so earlier interventions can be done in the orthopaedic clinic.
详细描述
The purpose of this study is to determine if diffusion MRI can be used for tissue characterization in childhood and adolescent growth plate injuries, and to get a better understanding of the physiologic disturbance of an injured physis
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Prospective
入排标准
- 年龄范围
- 8 Years 至 12 Years（Child）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Salter-Harris Type II, III, or IV fracture through the distal radius
- •Growth plates are open
- •Ages 8-12
- •Able to consent in English
排除标准
- •All fractures not sustained to distal radius
- •SH Type I or V fracture
- •Injury to contralateral limb
- •Previous injury to distal radius
- •Diseases known to alter bone healing or growth]
- •Contraindications to undergoing an MRI scan
结局指标
主要结局
Tissue characterization of growth plate using diffusion MRI
时间窗: 4-6 weeks following injury
Diffusion MRI scan of injured and contralateral (control) physis.
次要结局
未报告次要终点