DRKS00019938已完成不适用
on-interventional observational study on the use of autologous platelet-rich fibrin membranes in the therapy of antiresorbiva-associated necrosis of the jaw - APANK
niversitätsklinikum Schleswig-Holstein (UKSH)0 个研究点目标入组 52 人开始时间: 2020年1月14日最近更新:
适应症
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 52
研究概览
简要总结
暂无简介。
研究设计
- 研究类型
- Observational
入排标准
- 年龄范围
- 18 Years 至 100 Years（—）
- 性别
- All
入选标准
- •Patients undergoing MRONJ in stage 1, 2 or 3 according to the criteria of AAOMS
- •- Previous or current use of bisphosphonates or RANK-L inhibitors subcutaneously or intravenously in malignant disease
- •- Peri- and posttherapeutic intravenous high-dose antibiotics until the 5th day postoperative using Unacid 3g i.v. 1-1-1
- •- Peri- and post-therapeutic diet by means of nasogastric probe food
排除标准
- •- positive history of radiation in the head and neck area
- •- MRONJ Diagnosis without Clinical Exposure of Exposed Jaw Bone (Stage 0)
- •- microvascular reconstruction in the head and neck area
- •- Patients with renovations under local anesthesia
- •- Hemorrhagic diathesis or thrombocytopenia <150,000 / µl
研究者
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