跳至主要内容
临床试验/NCT00563888
NCT00563888Unknown不适用

Change of Neural Network Indicators Through Narrative Treatment of PTSD in Torture Victims

University of Konstanz1 个研究点 分布在 1 个国家目标入组 30 人开始时间: 2007年1月1日最近更新:
适应症
干预措施

试验速览

阶段
不适用
发起方
入组人数
30
试验地点
1
主要终点
PTSD diagnosis and severity score according to the Clinicians Administered PTSD Scale (CAPS)

研究概览

简要总结

Effective Treatment of PTSD involves talking about the traumatic event in detail.It is unclear how this process influences the sensory-specific trauma network (fear structure)in the traumatized person. The goal of the project is to test the hypothesis that treatment-facilitated recovery does not change the original fear structure but establishes an inhibitory mechanism that depends on verbal activity. An affective visual steady-state paradigm in magnetencephalography (MEG) using positive, aversive and neutral picture stimuli will be used to examine the spatial and temporal pattern of the processing of emotional stimuli. To examine the effects of treatment this paradigm will be used as outcome measure within a randomized controlled trial of Narrative Exposure Therapy and a waiting-list control condition for severely traumatized torture victims.

研究设计

研究类型
Interventional
分配方式
Randomized
干预模型
Parallel
主要目的
Treatment
盲法
Single (Outcomes Assessor)

入排标准

年龄范围
18 Years 至 65 Years(Adult, Older Adult)
性别
All
接受健康志愿者
否

入选标准

  • •experiences of organized violence/torture
  • •PTSD diagnosis

排除标准

  • •psychotic disorder
  • •neurological disease or seizures
  • •current drug/alcohol abuse

研究组 & 干预措施

A

Experimental

Narrative Exposure Therapy (NET)

干预措施: NET (Behavioral)

B

No Intervention

Waitinglist Control Group

结局指标

主要结局

PTSD diagnosis and severity score according to the Clinicians Administered PTSD Scale (CAPS)

时间窗: 4 & 9 months after completion of treatment

次要结局

  • steady state visual evoked magnetic fields in response to affective stimuli(4 & 9 months after completion of treatment)

研究者

发起方
University of Konstanz
申办方类型
Other

研究点 (1)

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