NCT03502083已完成不适用
Vasodilatory Effect of GLP-1
适应症
相关药物
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 11
- 主要终点
- Forearm bloodflow ratio with GLP-1
研究概览
简要总结
Comprehensive assessment of human vasodilatory effect of GLP-1 in forearm and coronary arteries
研究设计
- 研究类型
- Interventional
- 分配方式
- Non Randomized
- 干预模型
- Single Group
- 主要目的
- Basic Science
- 盲法
- None
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Waiting list for elective PCI to LAD Able to give informed consent Over 18
排除标准
- •GLP-1 based therapy Insulin Calcium channel blockers Nicorandil Nitrates
结局指标
主要结局
Forearm bloodflow ratio with GLP-1
时间窗: Change from baseline
Peripheral vasodilatory response of GLP-1
Change in IMR (index of microcirculatory resistance) with GLP-1 compared with baseline
时间窗: Change from baseline
Change in coronary microcirculatory resistance from baseline
次要结局
未报告次要终点
研究者
相似试验
进行中（未招募）
1 期
Effect of GLP-1 on microvascular function in patients with type 2 diabetesEUCTR2012-005013-38-DK20
已完成
4 期
Effect of Glucagon-like Peptide 1 (GLP-1) on Microvascular Myocardial Function in Patients With Type 2 Diabetes.Microvascular DysfunctionType 2 DiabetesNCT01931982Bispebjerg Hospital20
Unknown
不适用
Investigation of Vasodilation and Intensity of Headache Triggered by Glucagon Like Peptide-1 in HumansHeadache, MigraineNCT04232605Danish Headache Center43
已完成
不适用
Glucagon-like Peptide 1 (GLP-1) and Endothelial Dysfunction in Metabolic SyndromeMetabolic SyndromeNCT00856700University of Rome Tor Vergata20
已完成
4 期
Cardiovascular Effects of GLP-1 Receptor ActivationObesityPreDiabetesNCT03101930Vanderbilt University Medical Center329