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临床试验/NCT06976398
NCT06976398已完成不适用

Investigation of Central Sensitisation in Patients With Chronic Non-spesific Neck Pain

Karabuk University2 个研究点 分布在 2 个国家目标入组 83 人开始时间: 2025年5月8日最近更新:

试验速览

阶段
不适用
状态
已完成
发起方
入组人数
83
试验地点
2
主要终点
Proprioception

研究概览

简要总结

Chronic neck pain is one of the musculoskeletal pain problems that can cause chronic disability. It is emphasised that individuals with chronic neck pain have difficulty during different activities in their daily lives, and that this problem is a very common health problem that can lead to disability. In the case of chronic neck pain, changes in the pain threshold cause central sensitisation and individuals become more sensitive to pain stimuli. This situation can affect the processing of proprioceptive information and lead to deterioration in proprioceptive perception. This situation leads to perceptual problems in body and neck awareness. Therefore, examining the relationship between the relevant parameters is important in the rehabilitation process. In this context, the aim of the study is to examine the relationship between body awareness and pain, central sensitisation, disability and proprioception in patients with chronic non-specific neck pain.

详细描述

Chronic neck pain is a common pain problem related to the musculoskeletal system and can lead to permanent (chronic) disability over time. In approximately 50-85% of individuals with neck pain, complaints do not completely improve despite treatment, causing the pain to become chronic. Individuals with chronic neck pain have difficulty performing various activities in their daily lives, and this negatively affects their quality of life. Proprioceptive feedback in the neck region, that is, sensory information that allows the body to perceive its position in space, is very important for proper control of head and neck movements. However, chronic pain can lead to a condition called central sensitization. In this case, the individual's pain threshold decreases and they become more sensitive to stimuli that would normally not cause pain. This increased sensitivity can make it difficult for the brain to process proprioceptive information correctly, which can lead to impairments in body and neck awareness. Therefore, investigating the relationship between body awareness and pain level, central sensitization, disability status and proprioception in individuals with chronic non-specific neck pain is of great importance in terms of developing an effective rehabilitation program.

研究设计

研究类型
Observational
观察模型
Case Only
时间视角
Cross Sectional

入排标准

年龄范围
18 Years 至 65 Years(Adult, Older Adult)
性别
All
接受健康志愿者

入选标准

  • Being between the ages of 18-65
  • Being diagnosed with chronic non-specific neck pain by a doctor
  • Being willing to participate in the study

排除标准

  • Having psychological disorders, mental disorders, cancer and severe depression
  • Having a history of traumatic injury
  • Having a history of primary or metastatic spinal malignancy, spinal fracture
  • Having a neurological disease (Hemiplegia, Multiple Sclerosis, Parkinson's, etc.)
  • Having been diagnosed with advanced osteoporosis
  • Having a history of surgical intervention or acute infection in the cervical region

研究组 & 干预措施

Higher sensitization

It will consist of patients who exceed the cut-off score according to the central sensitization scale score.

Normal sensitization

It will consist of patients with a central sensitization scale score lower than the cut-off score.

结局指标

主要结局

Proprioception

时间窗: Baseline

Proprioception will be recorded as the degree of deviation with the CROM device. As the degree of deviation increases, proprioception worsens.

Body awareness

时间窗: Baseline

Body Awareness Questionnaire (BAF) will be used. It varies between 18-126 points and as the score decreases, awareness decreases.

Central sensitization

时间窗: Baseline

It will be evaluated with the "Central Sensitization Scale". The scale is scored between 0-100 and 40 points and above is recorded as sensitive.

Pain severity

时间窗: Baseline

Pain intensity will be assessed with the Numerical Pain Scale. It is scored between 0-10 and the higher the score, the greater the pain intensity.

Pain threshold

时间窗: Baseline

Pain threshold will be assessed with an algometer. An increase in the applied pressure indicates a higher pain threshold.

Neck disability

时间窗: Baseline

Neck disability will be evaluated with the index. It varies between 0-50 points and the higher the score, the higher the disability.

Neck awareness

时间窗: Baseline

It will be assessed with the Fremantle Neck Awareness Questionnaire. It varies between 0-36 and as the score increases, awareness decreases.

次要结局

未报告次要终点

研究者

发起方
Karabuk University
申办方类型
Other
责任方
Principal Investigator
主要研究者

Musa Güneş

Principal Investigator, PhD

Karabuk University

研究点 (2)

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