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临床试验/NCT02942472
NCT02942472Unknown不适用

Position Of The Tip Of The Inner Catheter And Air Bubbles As Predictors Of Pregnancy During ICSI Cycles:Prospective Observational Study

Ain Shams Maternity Hospital0 个研究点目标入组 94 人开始时间: 2016年10月最近更新:
适应症

试验速览

阶段
不适用
入组人数
94
主要终点
clinical pregnancy rate

研究概览

简要总结

Position of the tip of the inner catheter and air bubbles detection (at time,5min 10min)during embryo transfer influence the pregnancy rate in ICSI cycles .

详细描述

The aim of this study is to assess the relationship between the position of the tip of the inner catheter, the position of the air bubbles (at time , 5 min ,10 min )after embryo transfer and pregnancy rate outcome in ICSI cycles. Most IVF teams consider not touching the endometrium and the uterine fundus with replacement of the embryos in the lumen of the endometrial cavity the most important factors for successful embryo transfer, it is highly recommended to use agents that can facilitate a smooth embryo transfer and reduce unintended stimulation of the fundus, for example the application of soft-tipped catheters, which can improve pregnancy rate.

The advantage of using the air and liquid content for catheter loading is to prevent the embryo from adhering to the wall of the catheter at the time of injection.The presence of two air bubbles on both sides of the medium that contains the embryo prevents the transfer of the embryo within the catheter and beside, in the transfer under ultrasonographic guidance, the air bubbles are often considered a marker for the embryo's position in the uterus.

研究设计

研究类型
Observational
观察模型
Case Only
时间视角
Prospective

入排标准

年龄范围
20 Years 至 40 Years(Adult)
性别
Female
接受健康志愿者

入选标准

  • BMI < 30 kg/ m
  • Between 20 and 35years old.
  • FSH levels on cycle day 3 of <12 mIU/mL.
  • Both ovaries present deprived of morphological abnormalities and adequately visualized in Transvaginal ultrasound.
  • Grade one or two embryo quality.

排除标准

  • Hydrosalpinx.
  • Intrauterine lesion.
  • Patients undergoing ET after cryopreservation.
  • Blood present on the catheter during the transfer procedure.
  • A difficult transfer or with a suspicion of touching the fundus.
  • Endometrial thickness less than 8mm.
  • Known allergic reaction against one of the ingredient of the medications used during the study.

结局指标

主要结局

clinical pregnancy rate

时间窗: one and half year

次要结局

未报告次要终点

研究者

申办方类型
Other
责任方
Principal Investigator
主要研究者

AMR HELMY YEHIA

Associate Professor

Ain Shams Maternity Hospital

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