Develop a Novel Occupational Training Program for Schizophrenia Patients Based on Virtual Reality Techniques
试验速览
- 阶段
- 不适用
- 状态
- 招募中
- 入组人数
- 40
- 试验地点
- 1
- 主要终点
- clinical ratings of schizophrenia symptoms
研究概览
简要总结
Establish a novel vocational training program and test its validity in a pilot study.
详细描述
40 schizophrenia patients will be recruited to join the virtual reality based vocational training program, the training effect will be compared by interview skills and problem solving before and after the training.
研究设计
- 研究类型
- Interventional
- 分配方式
- Non Randomized
- 干预模型
- Sequential
- 主要目的
- Treatment
- 盲法
- None
入排标准
- 年龄范围
- 20 Years 至 40 Years（Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Having a diagnosis of schizophrenia based on the Diagnostic and Statistical Manual of Mental Disorders -5th version
- •Aged between 20 and 55 years.
- •Motivated to have a job.
- •Having a full-scale IQ > 70 on the Wechsler Adult Intelligence Scale-version IV.
- •Having a PANSS positive scale < 70, indicating a stable condition during the illness course.
排除标准
- •Comorbid with other major psychiatric disorders (i.e., bipolar disorders) or neurological diseases.
- •Substance abuse within one year.
- •Visual impairment and/or hearing impairment that would preclude participation in the VR-based training program.
研究组 & 干预措施
Mild ED/NS
10 patients with mild or none executive function impairment and mild or none negative symptoms.
干预措施: VR-assisted occupational training (Behavioral)
Mild ED/Severe NS
10 patients with mild or none executive function impairment and severe or moderate negative symptoms.
干预措施: VR-assisted occupational training (Behavioral)
Severe ED/Mild NS
10 patients with severe or moderate executive function impairment and mild or none negative symptoms.
干预措施: VR-assisted occupational training (Behavioral)
Severe ED/NS
10 patients with severe or moderate executive function impairment and severe or moderate negative symptoms.
干预措施: VR-assisted occupational training (Behavioral)
结局指标
主要结局
clinical ratings of schizophrenia symptoms
时间窗: 8 weeks
The Positive and Negative Syndrome Scale (PANSS) is a 30-item rating scale completed by trained research staff. Scores for positive, negative, cognitive disorganization, emotional discomfort, and hostility/excitement symptoms were derived from factor-derived scoring published. \* There are 30 different symptoms rated from 1 to 7 (total score of 210). Higher the score, worse the symptoms
vocational skills
时间窗: 8 weeks
Job interview role-play performance will be scored across nine domains: conveying oneself as a hard worker, sounding easy to work with, conveying that one behaves professionally, negotiation skills (requesting one day off), sharing things in a positive way, sounding honest, sounding interested in the position, comfort level, and establishing rapport
global improvement
时间窗: 8 weeks
Clinical Global Impression Improvement scale (CGI-I) rating scales are commonly used measures of symptom severity, treatment response and the efficacy in treatment studies of patients with mental disorders. It is a 7-point scale that require clinician to assess how much the patient's illness has improved or worsened relative to baseline. "1" meaning very much improved, "7" meaning very much worsen.
次要结局
未报告次要终点