Avastin as an Adjunct to Diode Laser Cyclophotoablation in the Treatment of Neovascular Glaucoma
试验速览
- 阶段
- 2 期
- 状态
- 已完成
- 入组人数
- 16
- 试验地点
- 1
- 主要终点
- Disappearance of iris neovessels
研究概览
简要总结
Assess the efficacy of Avastin as an adjunct to Diode Laser cyclophotocoagulation in the treatment of Neovascular Glaucoma.
详细描述
Design: Prospective, comparative interventional case series. Method: Patients were randomly assigned into Group A which were treated with Diode laser cyclophotocoagulation alone, whereas group B received intravitreal Avastin (One milligram = 0.04mL of 25 mg/mL) in conjunction with the Diode Laser. The preoperative data included etiology, mean age; follow up period, and a full ophthalmological examination with emphasis on mean IOP, iris neovascularization, pain and corneal edema.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- None
入排标准
- 年龄范围
- 14 Years 至 72 Years（Child, Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Neovascular absolute glaucoma
- •Painful blind eyes
排除标准
- •Neovascular glaucoma with useful vision or potential for useful vision
研究组 & 干预措施
Avastin , diode laser cyclophotcoagulation
Intravitreal Avastin injection in conjunction with diode laser cyclophotocoagulation
干预措施: Diode laser cyclophotocoagulation enhanced by intravitreal injection of Avastin (Procedure)
Diode Laser cyclophotocoagulation
Diode laser cyclophotocoagulation to control intraocular pressure
干预措施: Diode laser cyclophotocoagulation enhanced by intravitreal injection of Avastin (Procedure)
结局指标
主要结局
Disappearance of iris neovessels
时间窗: 2 weeks
次要结局
- Intra ocular pressure(4 weeks)