Optimal Antiplatelet Therapy for Chinese Patients With Coronary Artery Disease
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 14,032
- 试验地点
- 107
- 主要终点
- Major adverse cardiac and cerebral events
研究概览
简要总结
Antiplatelet therapy is the cornerstone for the prevention of atherothrombosis in patients with coronary artery disease (CAD). However, the efficacy and safety of antiplatelet therapy are varied due to ethnic and/or individual variability. The aim of the OPT-CAD study was to demonstrate contemporary status and outcomes of antiplatelet therapy in Chinese CAD patients, and to explore predictors of ischemic or bleeding events in such cohort.Patients above 18 years old who were diagnosed as CAD and received antiplatelet therapy were prospectively enrolled in this national wide, non-intervention registry. All medications and laboratory tests were physician discretion.
详细描述
Antiplatelet therapy is the cornerstone for the prevention of atherothrombosis in patients with coronary artery disease (CAD). However, the efficacy and safety of antiplatelet therapy are varied due to ethnic and/or individual variability. The aim of the OPT-CAD study was to demonstrate contemporary status and outcomes of antiplatelet therapy in Chinese CAD patients, and to explore predictors of ischemic or bleeding events in such cohort.Patients above 18 years who were diagnosed as CAD and received antiplatelet therapy were prospectively enrolled in this national wide, non-intervention registry. All medications and laboratory tests were at physician discretion.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Prospective
入排标准
- 年龄范围
- 18 Years 至 85 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- 未提供
排除标准
- •With severe disease and life expectancy for 6 months or less
- •Difficult to attain follow-up situations judged by researchers (travel, speech or mental disorder, etc.)
- •Taking part in an interventional clinical research
结局指标
主要结局
Major adverse cardiac and cerebral events
时间窗: 12month
a composite of all cause death, myocardial infarction, stroke or any revascularization or stroke
次要结局
- recurrent angina(12 month)
- all cause death(12month)
- stroke(12 months)
- Stent thrombosis(12 month)
- rehospitalization(12 month)
- any bleeding events(12 month)
- myocardial infarction(12 months)
- any revascularization(12 months)
研究者
Han Yaling
Dr
Shenyang Northern Hospital