NCT03581695已完成不适用
Inflammatory Biomarkers of Pediatric Pulmonary Hypertension: a Prospective Cohort Study
适应症
干预措施
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 74
- 试验地点
- 2
- 主要终点
- Measurement of HGMB1
研究概览
简要总结
To investigate if the inflammatory protein, high mobility group box 1 (HMGB1), along with other inflammatory mediators, is elevated in pediatric patients with congenital heart disease (CHD) and pulmonary hypertension as compared to those with CHD alone, or with healthy controls.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Prospective
入排标准
- 年龄范围
- 1 Day 至 18 Years（Child, Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •patients of any age with congenital cardiac disease coming for catheterization of the right heart, or both the right and left heart.
排除标准
- •active systemic infection
- •current active cancer
- •active cancer treatment
- •prior bone marrow transplant
- •prior solid organ transplant
研究组 & 干预措施
Pulmonary Hypertension and Congenital Heart Disease
Pulmonary Hypertension and Congenital Heart Disease
干预措施: Blood test (Other)
Congenital Heart Disease
Congenital Heart Disease
干预措施: Blood test (Other)
Healthy Controls
Healthy Controls
干预措施: Blood test (Other)
结局指标
主要结局
Measurement of HGMB1
时间窗: 1 day
Measurement of HGMB1
次要结局
未报告次要终点
研究者
Katherine Taylor
Staff Anesthesiologist
The Hospital for Sick Children
研究点 (2)
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