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临床试验/NCT06044961
NCT06044961已完成不适用

Radiomics-based Models for the Prediction of Pathological Response to Neoadjuvant Therapy in Gastric and Gastroesophageal Cancer

Fondazione Policlinico Universitario Agostino Gemelli IRCCS0 个研究点目标入组 80 人开始时间: 2005年1月1日最近更新:
适应症

试验速览

阶段
不适用
状态
已完成
入组人数
80
主要终点
Use of radiomics

研究概览

简要总结

Identifying predictors of response to neoadjuvant therapy in gastric and gastro-oesophageal cancer early in the history of the disease would ensure optimal treatment planning.

The study aims to apply radiomics for the prediction of response to neoadjuvant therapy.

研究设计

研究类型
Observational
观察模型
Other
时间视角
Retrospective

入排标准

性别
All
接受健康志愿者

入选标准

  • Patients with locally advanced stomach cancer undergoing neoadjuvant chemotherapy and gastrectomy between January 2005 and August 2022

排除标准

  • Siewert 1 tumors;
  • Patients who have received neoadjuvant with the addition of a biological drug;
  • Patients who have received radiotherapy;
  • Patients without staging CT scan or with insufficient image quality in terms of phases performed, pixel spacing, slide thickness (mandatorily: > 5 mm) or artefacts.

结局指标

主要结局

Use of radiomics

时间窗: 1 month

Apply radiomics for predicting response to neoadjuvant therapy.

次要结局

未报告次要终点

研究者

申办方类型
Other
责任方
Principal Investigator
主要研究者

Agnes Annamaria

MD

Fondazione Policlinico Universitario Agostino Gemelli IRCCS

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