CTRI/2011/091/000042已完成2 期
Study of efficacy of of 4-weeks doxycycline in patients of moderate to severe chronic obstructive pulmonary disease with stable symptoms-a randomized, open-labeled, pilot trial
Govt Medical College0 个研究点目标入组 72 人开始时间: 待定最近更新:
试验速览
- 阶段
- 2 期
- 状态
- 已完成
- 发起方
- 入组人数
- 72
研究概览
简要总结
暂无简介。
研究设计
- 研究类型
- Interventional
入排标准
入选标准
- •1.Age > 40 years
- •2.Smoking history >10 packs years
- •3.Patients classified as GOLD criteria II and III
- •4.Ability to perform Pulmonary function tests
排除标准
- •1.Patient with acute exacerbation (Anthonisen et al) / critically ill patients
- •2.Patient with moderate/severe exacerbation in last 4 weeks as defined by severity scale proposed by Cazzola et al.
- •3.Patient with active respiratory disease other than COPD (tuberculosis, lung malignancies, Bronchiectasis, pneumonia, bronchial asthma)
- •4.Patient with acute systemic/local infection
- •5.Patient with cardiac disease (CCF, Recent myocardial infarction, Cardiac arrhythmias)
- •6.Patient with gastrointestinal disorders (Gastro-esophageal reflux disorder, peptic ulcer, Undiagnosed abdominal pain)
- •7.Patient with renal or hepatic impairment
- •8.Patient with h/o hypersensitivity to tetracyclines
- •9.Patient receiving oral corticosteroids
研究者
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